QUINOLINE-4-CARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 486-74-8 |
| Product name | QUINOLINE-4-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for QUINOLINE-4-CARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk QUINOLINE-4-CARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of QUINOLINE-4-CARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antimalarial drug intermediates | Serves as a key precursor for quinoline-based compounds in the synthesis of chloroquine or hydroxychloroquine |
| Pharmaceuticals | Development of antimicrobial and anticancer agents | Used to construct biologically active heterocyclic structures via coupling reactions to introduce target molecules |
| Pesticides | Intermediate for agricultural fungicides | Participates in the construction of nitrogen-containing heterocyclic pesticide molecules to enhance biological stability |
| Organic Synthesis | Organic synthesis intermediate | Applied in Suzuki coupling, esterification, amidation, and other reactions to prepare functionalized quinoline derivatives |
| Materials Science | Synthesis of fluorescent probes and functional materials | Used as a ligand or structural scaffold in designing metal-ion sensors or optoelectronic materials |
Manufacturing Quality Control of QUINOLINE-4-CARBOXYLIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV or HPLC-DAD | Separation and detection of structurally related impurities (e.g., quinoline, 4-hydroxyquinoline, decarboxylation products) using gradient elution and diode-array detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., methanol, ethyl acetate, toluene) against calibrated standards. |
| Heavy Metals | ICP-MS or ICP-OES | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, based on elemental mass-to-charge ratio (ICP-MS) or atomic emission intensity (ICP-OES). |
| Chloride Content | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity by comparison to reference value (198–200 °C). |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of crystalline form and color intensity against platinum-cobalt standard solutions (APHA units) under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after high-temperature ashing (700–800 °C) and cooling in desiccator. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH determination of saturated aqueous suspension (e.g., 1% w/v) using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine volumetric particle size distribution based on light scattering pattern. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through solution; used to confirm chiral integrity (though quinoline-4-carboxylic acid is achiral, may detect chiral contaminants). |
Technical Specifications of QUINOLINE-4-CARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 174-178°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of QUINOLINE-4-CARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of QUINOLINE-4-CARBOXYLIC ACID
Packaging of QUINOLINE-4-CARBOXYLIC ACID
Industrial QUINOLINE-4-CARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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