N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 487048-28-2 |
| Product name | N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral building block for constructing proline-containing drug molecules (e.g., protease inhibitors, antiviral agents) | Key intermediate in solid-phase or solution-phase peptide synthesis via peptide coupling or cyclization reactions |
| Chemical Synthesis | Preparation of stereoselective cyanoproline derivatives | Derivatization into other functionalized amino acid analogues through deprotection, ester hydrolysis, or cyano group transformation in organic solvents |
| Research Reagents | Structure–activity relationship (SAR) studies in biochemistry and medicinal chemistry | Used as a reference standard or intermediate for chiral molecular structure verification in analytical methods such as HPLC and NMR |
Manufacturing Quality Control of N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-220 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., trans isomer, hydrolysis/degradation products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Measures residual solvents (e.g., methanol, ethyl acetate, toluene) by headspace GC with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Optical Rotation | [alpha]D | Measures specific optical rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, As, Hg, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residual Palladium | ICP-MS | Measures palladium residue from catalytic hydrogenation steps via microwave-assisted digestion followed by ICP-MS analysis. |
| Particle Size Distribution | Laser Diffraction | Determines dry powder particle size distribution by analyzing laser light scattering pattern of dispersed sample. |
| Melting Point | Capillary Melting Point Apparatus | Identifies melting range using controlled heating of capillary-packed sample observed visually or via automated optical detection. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying under specified temperature/vacuum conditions. |
| Microbial Limits | Membrane Filtration | Assesses bioburden by filtering solution through membrane, then culturing on soybean-casein digest agar and sabouraud dextrose agar. |
Technical Specifications of N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 85–89°C |
| Optical Rotation | -15.0 to -19.0° (c=1, in CHCl3) |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER
Safety Information of N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER
Industrial N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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