4-Bromomethyl-1,2-dihydroquinoline-2-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4876-10-2 |
| Product name | 4-Bromomethyl-1,2-dihydroquinoline-2-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromomethyl-1,2-dihydroquinoline-2-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromomethyl-1,2-dihydroquinoline-2-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromomethyl-1,2-dihydroquinoline-2-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of quinoline-based drug intermediates | Used as a brominating reagent in cyclization reactions to construct nitrogen-containing heterocyclic structures |
| Agrochemicals | Intermediate for fungicide and insecticide synthesis | Introduces the quinolyl group via nucleophilic substitution to enhance biological activity |
| Organic Synthesis | Organic synthesis intermediate | Applied in constructing complex molecular frameworks and participating in transition metal-catalyzed reactions such as Suzuki coupling and Heck reactions |
Manufacturing Quality Control of 4-Bromomethyl-1,2-dihydroquinoline-2-one
| Detection Item | Common Detection Method | Method Overview |
|---|---|---|
| Content Determination | HPLC (High-Performance Liquid Chromatography) | Uses a reverse-phase column (e.g., C18), UV detector (wavelength around 254–280 nm), and quantifies the main component content using external standard or internal standard methods, offering high sensitivity and good reproducibility. |
| Related Substances (Impurities) | HPLC (High-Performance Liquid Chromatography) | Separates the main component from various organic impurities (such as starting materials, intermediates, and degradation products) using a gradient elution program. Impurity content is calculated by peak area normalization or by comparison with reference substances. |
| Residual Solvents | GC (Gas Chromatography) | According to ICH guidelines, detects volatile organic solvents used in production (e.g., methanol, ethanol, dichloromethane, ethyl acetate, etc.), typically using headspace sampling combined with an FID detector. |
| Moisture | Karl Fischer Titration | Divided into volumetric method or coulometric method, precisely determines the moisture content in the sample, suitable for quinolone compounds sensitive to moisture. |
| Melting Point | Melting Point Determination | Measures the melting temperature range of the compound using a melting point apparatus or capillary method, used to assess purity and crystalline form consistency. |
| Crystalline Form Analysis | X-ray Powder Diffraction (XRD) | Analyses the crystal structure of solid samples to identify the presence of polymorphic forms, ensuring crystalline form consistency across batches. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FTIR) | Determines infrared absorption spectra of the sample by KBr pellet or using an ATR attachment, comparing with standard spectra to confirm molecular structure and characteristic functional groups. |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR and/or ¹³C-NMR | Solves the sample in deuterated solvent and uses NMR spectra to verify chemical structure, particularly useful for determining substituent positions and assessing purity. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or ICP-MS | Detects residual heavy metals such as lead, cadmium, mercury, and arsenic, complying with limit requirements for pharmaceutical excipients or active pharmaceutical ingredients (e.g., Chinese Pharmacopoeia or USP standards). |
| Residue After Incineration | Sulfuric Acid Ignition Method | Weighs the residue after high-temperature incineration to evaluate the total amount of inorganic impurities, commonly used for purity evaluation of raw materials. |
Technical Specifications of 4-Bromomethyl-1,2-dihydroquinoline-2-one
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromomethyl-1,2-dihydroquinoline-2-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromomethyl-1,2-dihydroquinoline-2-one
Safety Information of 4-Bromomethyl-1,2-dihydroquinoline-2-one
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4-Bromomethyl-1,2-dihydroquinoline-2-one
Industrial 4-Bromomethyl-1,2-dihydroquinoline-2-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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