2,4,5-Trimethoxybenzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 490-64-2 |
| Product name | 2,4,5-Trimethoxybenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4,5-Trimethoxybenzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4,5-Trimethoxybenzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4,5-Trimethoxybenzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), including antibiotics and anti-inflammatory agents | Prepared via organic synthesis reactions such as esterification, reduction, and coupling to construct target drug molecules |
| Pesticides | Used as an intermediate in the synthesis of certain herbicides and fungicides | Tri-methoxybenzoic acid structural units are introduced via aromatic substitution reactions |
| Fragrances & Flavors | Used as an intermediate in fragrance synthesis to impart specific olfactory characteristics | Floral- or fruity-odor derivatives are generated via esterification or condensation reactions |
| Polymers & Advanced Materials | Used as a functional monomer in the synthesis of specialty polymers or resins | Incorporated into polymer chain construction via condensation or addition polymerization |
| Fine Chemicals | Used in the production of fluorescent dyes, optoelectronic materials, and other high-performance chemicals | Molecular structures with tailored electronic properties are built through multi-step organic synthesis |
Manufacturing Quality Control of 2,4,5-Trimethoxybenzoic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water (containing a small amount of acid such as phosphoric acid or formic acid) as the mobile phase. Detection is performed using a UV detector (typically at 254–280 nm), and the main component is quantified by external or internal standard method. |
| Purity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Suitable for volatile or derivatizable samples. Derivatization (e.g., methylation) enhances volatility. After separation by gas chromatography, components are detected by mass spectrometry to identify impurities and evaluate purity. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Uses ¹H-NMR and ¹³C-NMR to confirm compound structure. The 2,4,5-trimethoxy substitution pattern and presence of the carboxyl group are verified through characteristic chemical shifts, coupling constants, and integration areas of the peaks. |
| Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Uses the same conditions as assay testing. Organic impurities (e.g., unreacted starting materials, intermediates, degradation products) are identified by comparing retention times and quantified by peak area. Total impurities are typically required to be below 0.5%. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, headspace sampling coupled with gas chromatography is used to detect residual organic solvents (e.g., methanol, ethanol, acetone, dichloromethane) from the manufacturing process. Quantification is performed using an FID detector. |
| Water Content | Karl Fischer Titration | Performed by volumetric or coulometric method to accurately determine moisture content in samples. Essential for quality control of moisture-sensitive active pharmaceutical ingredients, with a typical requirement of ≤0.5% water. |
| Melting Point | Capillary Melting Point Method | Sample is packed into a capillary tube and heated gradually in a melting point apparatus to observe the initial and complete melting temperatures. The typical melting range for 2,4,5-trimethoxybenzoic acid is approximately 178–182°C, used for preliminary identification and purity assessment. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, atomic absorption spectroscopy or inductively coupled plasma mass spectrometry (ICP-MS) is used to measure residual heavy metals such as lead, arsenic, cadmium, and mercury. Levels must comply with pharmacopeial limits (e.g., ≤10–20 ppm). |
| Polymorphic Form Analysis (if applicable) | X-Ray Diffraction (XRD) | Used to identify crystalline forms in polymorphic substances, ensuring consistency of crystal form across batches, which affects solubility and stability. |
| Particle Size Distribution (if applicable) | Laser Particle Size Analysis | Measures particle size distribution of solid powder samples, important for controlling dissolution rate and uniformity in formulation processes. |
Technical Specifications of 2,4,5-Trimethoxybenzoic acid
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 152–156 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4,5-Trimethoxybenzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4,5-Trimethoxybenzoic acid
Packaging of 2,4,5-Trimethoxybenzoic acid
Industrial 2,4,5-Trimethoxybenzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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