China Factory Direct
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| CAS number | 490-78-8 |
| Product name | 2',5'-Dihydroxyacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of the antifungal agent terbinafine | Used in the multi-step organic synthesis of terbinafine via reduction, cyclization, and related reactions |
| Cosmetics | UV absorber and antioxidant additive | Added as a stabilizer to sunscreens and skin care emulsions; requires dissolution and homogenization to ensure compatibility with the formulation matrix |
| Dyes | Intermediate in the synthesis of anthraquinone- and azo-based dyes | Participates in diazotization–coupling reactions or serves as a hydroxyl-substituted aromatic ring for constructing dye chromophores |
| Pesticides | Intermediate in the synthesis of fungicides and plant growth regulators | Used to construct active molecules containing an acetophenone moiety; target compounds are prepared via derivatization reactions such as chlorination and amination |
| Test Item | Common Testing Method | Method Overview |
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| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with reference spectra to confirm the presence of characteristic functional groups of 2,5-Dihydroxyacetophenone, such as phenolic hydroxyl and carbonyl groups. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase. Detect at UV wavelength of 240–280 nm and quantify the main component using external or internal standard method. |
| Related Substances (Impurity) Test | High-Performance Liquid Chromatography (HPLC) | Similar conditions as assay, but with optimized gradient or isocratic elution to effectively separate and detect potential impurities such as synthesis by-products or degradation products. Impurity levels are calculated using area normalization or self-dilution control methods. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Loss on Drying at Atmospheric Pressure | Dry the sample at a specified temperature (e.g., 105°C) to constant weight and measure the percentage weight loss to assess moisture and volatile content. |
| Sulfated Ash (Residue on Ignition) | High-Temperature Ignition Method | Ignite the sample at high temperature (typically 700–800°C), then weigh the residual inorganic matter to monitor inorganic impurities or catalyst residues. |
| Heavy Metals | Thioacetamide Method or Atomic Absorption Spectroscopy (AAS) | Determine residual heavy metals such as lead, cadmium, mercury, and arsenic using colorimetry (with thioacetamide color development) or instrumental methods (AAS/ICP-MS), ensuring compliance with pharmacopoeial or regulatory limits. |
| pH Value (if prepared as solution) | pH Meter Method | Prepare a solution of the sample at a defined concentration and measure its acidity or alkalinity using a calibrated pH meter to reflect free acid/base content or hydrolysis status. |
| Melting Point | Capillary Melting Point Method | Use a melting point apparatus to determine the temperature range from initial melting to complete melting, serving as an auxiliary indicator for purity and identity confirmation. |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 145–149°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.