China Factory Direct
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| CAS number | 490-91-5 |
| Product name | THYMOQUINONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antibacterial and antifungal agents; research on natural product derivatives | Used as an active ingredient in in vitro antimicrobial assays; employed in chemical modification to synthesize novel antibacterial compounds |
| Food | Natural food preservative (limited application) | Added to oxidation-prone foods such as oils and seasonings to inhibit microbial growth and rancidity |
| Cosmetics | Preservative and antioxidant | Incorporated into emulsions, creams, and other formulations to replace conventional preservative systems and reduce skin irritation |
| Agriculture | Botanical pesticide active ingredient | Formulated into microemulsions or wettable powders for controlling fungal diseases in fruits and vegetables (e.g., gray mold) |
| Test Item | Common Testing Method | Method Overview |
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| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase under gradient or isocratic elution. Detection is performed at around 254 nm using a UV detector for quantitative analysis of thymoquinone content. This method offers high sensitivity and good reproducibility, making it the most commonly used technique in quality control. |
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Thymoquinone exhibits characteristic absorption peaks near 254 nm and 330 nm. Preliminary identification is achieved by comparing the UV spectra of the test sample with that of a reference standard. Simple to operate, this method is suitable for rapid screening. |
| Purity Test | Gas Chromatography (GC) or HPLC | For volatile samples or extracts, GC coupled with an FID detector can be used to analyze thymoquinone and its impurities. However, HPLC is more commonly employed for purity assessment, using either peak area normalization or external standard methods to evaluate purity. |
| Residual Solvents | Gas Chromatography (GC) | Determines residual organic solvents (e.g., methanol, ethanol, ethyl acetate) that may remain from the manufacturing process, in accordance with pharmacopoeial requirements. Quantitative analysis is typically performed using a headspace sampler coupled with GC/FID. |
| Moisture Content | Karl Fischer Titration | Accurately measures the water content in the sample, essential for raw material quality control to ensure stability. Available in volumetric and coulometric formats, this method provides high precision. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | By extending run time or optimizing gradient conditions, HPLC separates and detects degradation products or synthesis intermediates related to thymoquinone, thereby assessing the chemical stability of the sample. |
| Crystal Form Analysis | X-Ray Powder Diffraction (XRD) or Differential Scanning Calorimetry (DSC) | Used to analyze the crystalline structure and polymorphic forms of thymoquinone, ensuring consistency in physical properties between batches, which is critical for formulation performance. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (GC-MS) |
| Melting Point | 45.0–47.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic pungent odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.