China Factory Direct
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| CAS number | 4920-80-3 |
| Product name | 3-METHOXY-2-NITROBENZOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antibacterial drug intermediates | Prepared via nitration and methoxylation; used to construct benzoic acid-based antibacterial scaffolds |
| Pesticides | Synthesis of herbicide intermediates | Applied as an aromatic carboxylic acid derivative in coupling or amidation reactions to build active molecules |
| Dyes | Synthesis of azo dye intermediates | Subjected to diazotization-coupling to introduce nitro and methoxy substituents, thereby tuning dye hue and stability |
| Chemicals | Synthesis of precursors for organic luminescent materials | Applied as a nitro-substituted aromatic acid in condensation reactions to prepare fluorescent molecular scaffolds |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with mobile phases such as methanol/water or acetonitrile/buffer salt, and UV detection (e.g., 254 nm or 280 nm) for quantitative analysis of main component purity. Quantification is performed using external standard method or area normalization. |
| Content Determination | HPLC External Standard Method / Acid-Base Titration | HPLC method as above; titration method exploits the carboxylic acid properties by titrating with standardized sodium hydroxide solution, using phenolphthalein or potentiometric endpoint indication to calculate content. Suitable for rough content assessment of active pharmaceutical ingredients. |
| Related Substances (Impurity) Testing | HPLC Gradient Elution Method | Employs gradient elution program to separate the main peak from potential impurities (e.g., unreacted starting materials, by-products, degradation products). Impurity limits are set (e.g., individual impurity ≤0.5%, total impurities ≤1.0%). Requires validation of specificity and limit of detection. |
| Drying Loss | Drying Method (105°C, constant weight) | Sample is weighed into a pre-weighed, constant-weight container and dried at 105°C until constant weight is achieved. The percentage of mass loss is calculated to assess moisture and volatile substance content. |
| Melting Point Determination | Capillary Melting Point Apparatus Method | Sample is packed into a melting point capillary tube and heated at a controlled rate (e.g., 1–2°C/min). The temperature range from initial to complete melting is recorded, used for identification and preliminary purity assessment. |
| Residual Solvents | Gas Chromatography (GC) Headspace Injection | Based on ICH Q3C guidelines, uses headspace-GC-FID or GC-MS to quantitatively analyze organic solvents (e.g., methanol, ethyl acetate, DMF) that may remain from synthesis processes. |
| Heavy Metal Testing | Sulfuric Acetylamide Method (ChP) / ICP-MS | Traditional colorimetric method: sample digested and treated with chromogenic reagent, compared with lead reference solution; modern approach uses ICP-MS for precise determination of multiple metal elements (e.g., Pb, As, Cd, Hg). |
| Structural Confirmation | Infrared Spectroscopy (IR), Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS) | IR confirms functional groups (e.g., carboxyl, nitro, methoxy); ¹H/¹³C NMR elucidates hydrogen and carbon environments; MS (ESI or EI) determines molecular weight and fragmentation pattern. Combined data confirm compound structure. |
| pH Value (if applicable) | pH Meter Method | A solution of specified concentration (e.g., 1%) is prepared and measured directly using a calibrated pH meter to evaluate acidity strength, assisting in determining free acid state or salt form. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 148–152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.