China Factory Direct
|
|
| CAS number | 4961-40-4 |
| Product name | TRIETHYLENETETRAMINE TETRAHYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Synthetic Intermediate | Used as a protecting group or ligand auxiliary in peptide and drug molecule synthesis |
| Organic Synthesis | Ligand Reagent | Acts as a nitrogen-source ligand in metal-catalyzed reactions to facilitate complex formation |
| Materials Science | Resin Modifier | Applied to accelerate epoxy resin curing and enhance thermal stability and mechanical properties |
| Analytical Chemistry | Buffer and Masking Agent | Employed to adjust pH and mask interfering metal ions during metal ion analysis |
| Water Treatment | Chelating Agent Component | Used to chelate metal ions and control hardness ion concentration in water |
| Detection Item | Common Detection Method | Method Overview |
|---|---|---|
| Purity (Main Component) | HPLC (High-Performance Liquid Chromatography) | Using a C18 reversed-phase chromatographic column, with water-methanol or acetonitrile buffer (such as phosphate buffer) as the mobile phase, detected by a UV detector (210–220 nm), and quantified using external standard or internal standard methods. |
| Chloride Content | Ion Chromatography (IC) or Precipitation Titration | Ion Chromatography: Using an anion exchange column and conductivity detector to measure Cl⁻ concentration; Precipitation Titration: Using silver nitrate standard solution for titration, with potassium chromate as indicator, calculating chloride content based on the endpoint of AgCl precipitation. |
| Moisture Content | Karl Fischer Titration | The Karl Fischer reagent, consisting of iodine, sulfur dioxide, pyridine, and methanol, reacts quantitatively with water. The water content is determined by potentiometric or coulometric methods, suitable for precise determination of moisture in organic salts. |
| pH Value | Glass Electrode Method (pH Meter) | Prepare a 1% aqueous solution, and directly measure the pH value using a calibrated pH meter at 25°C, to evaluate acidity strength and integrity of the hydrochloride salt. |
| Ash Content (Residue after Combustion) | Combustion Weighing Method | Weigh the sample after high-temperature (500–600°C) combustion in a muffle furnace until constant weight is achieved. The percentage of inorganic residue relative to the original sample mass is calculated to assess inorganic impurity content. |
| Heavy Metal Content | Atomic Absorption Spectrometry (AAS) or ICP-MS | After acid digestion of the sample, AAS is used to determine the concentration of heavy metals such as Pb, Cd, As, and Hg, or ICP-MS is used for simultaneous detection of multiple elements, meeting pharmacopoeia or ICH limit requirements. |
| Appearance and Color | Visual Inspection + Colorimetric Measurement (Colorimetry) | Observe the sample as white to slightly yellow crystalline powder. Use a colorimeter or color chart for comparison to assess whether the color is abnormal due to impurities. |
| Solubility | Physical Dissolution Test | Determine the dissolution behavior in solvents such as water and ethanol. Tris(ethylenediamine) tetrahydrochloride should be soluble in water and sparingly soluble or insoluble in organic solvents, used for preliminary identification. |
| Melting Point or Decomposition Temperature | Melting Point Apparatus or Differential Scanning Calorimetry (DSC) | Determine the melting range using a melting point apparatus or analyze thermal behavior using DSC. Tris(ethylenediamine) tetrahydrochloride typically decomposes between 150–200°C, used for identification and purity assessment. |
| Related Substances (Impurity Profile) | HPLC-UV or LC-MS | Use gradient elution HPLC to separate and detect potential unreacted raw materials (e.g., triethylenetetramine), degradation products, or other organic impurities. LC-MS is used for structural identification. |
| Total Chloride Content (Total Cl) | Elemental Analysis (EA) or Ion Chromatography | Determine the elemental composition of C, H, N, and Cl using an elemental analyzer, and compare it with theoretical values to verify the stoichiometric ratio; or use IC method to calculate total chlorine content to confirm the structure of the tetrahydrochloride salt. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C (decomposes) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.2% |
| Heavy Metals | <=20 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.