China Factory Direct
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| CAS number | 4964-71-0 |
| Product name | 5-Bromoquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antimalarial, antitumor, and central nervous system drugs | Brominated quinoline structure introduced via quinoline bromination or cross-coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
| Agrochemicals | Nitrogen-containing heterocyclic intermediate for synthesizing high-efficacy insecticides and fungicides | Active molecular scaffold constructed from 5-bromoquinoline via nucleophilic substitution or metal-catalyzed coupling |
| Chemical Reagents | Halogenated heterocyclic reagent for organic synthesis; participates in metal-catalyzed coupling reactions | Serves as a bromine source or aryl ligand in palladium-catalyzed C–C and C–N bond formation |
| Materials Science | Precursor for luminescent materials, organic semiconductors, and functional dyes | Quinoline moiety incorporated via coupling polymerization or molecular design to modulate optoelectronic properties |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances (Impurities) | HPLC-UV or GC-FID | Separation and quantification of structurally related impurities (e.g., quinoline, bromobenzene, 5-bromoquinolinium salts) using retention time matching and response factor-corrected peak areas. |
| Residual Solvents | GC-FID with headspace sampling | Detection and quantification of volatile organic solvents (e.g., toluene, DMF, methanol) based on calibrated external standard curves in headspace vials. |
| Heavy Metals (as Pb) | ICP-MS or AAS (after acid digestion) | Quantification of total heavy metals (Pb, Cd, Hg, As, Cr) following microwave-assisted nitric/hydrogen peroxide digestion, based on atomic emission or absorption signals. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using standardized capillary tube method per USP <741> or Ph. Eur. 2.2.14. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based solvent. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Quantification of chloride ions after sample dissolution and extraction; IC separates Cl⁻ on an anion-exchange column with conductivity detection. |
| Appearance (Color & Clarity) | Visual Inspection in Nessler Cylinders | Assessment of solution clarity and color intensity against standard platinum-cobalt (APHA) scales after dissolving in specified solvent (e.g., ethanol). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 57–61°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.