China Factory Direct
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| CAS number | 49667-22-3 |
| Product name | 4-Methylsalicylamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Prepared via reaction of salicylic acid with methylamine |
| Pesticides | Intermediates for insecticides and herbicides | Used as an organic synthesis intermediate in constructing pesticide molecular structures |
| Fine fragrances | Fragrance additive | Applied in compounding fragrance products with specific odor profiles |
| Personal care & cosmetics | Antioxidant or preservative | Functioning as a stabilizing component in cosmetic formulations |
| Organic synthesis | Intermediate for synthesizing other organic compounds | Employed in further synthesis of complex organic molecules |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~230–280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., 4-methylsalicylic acid, unreacted salicylamide, hydrolysis/degradation products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace GC analysis with flame ionization detection (or mass spectrometry) to quantify residual solvents (e.g., methanol, ethanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in a non-aqueous medium. |
| Heavy Metals | ICP-MS or AAS (after acid digestion) | Quantification of toxic elements (e.g., Pb, Cd, Hg, As) following microwave-assisted acid digestion, using inductively coupled plasma mass spectrometry or atomic absorption spectroscopy. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of inorganic residue after charring and ashing at 500–600 °C, followed by precise weighing of the residual sulfate ash. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus; deviation from literature value (148–150 °C) indicates impurity or polymorphic variation. |
| Appearance & Color | Visual Inspection / Hazen (APHA) Color Scale | Subjective visual assessment against water or standard color solutions; APHA scale quantifies yellowness/browning indicative of degradation. |
| pH of Aqueous Suspension | pH Meter (10% w/v suspension in water) | Measurement of surface proton activity in a saturated aqueous suspension, reflecting acidic/basic impurities or hydrolytic instability. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine volumetric particle size distribution (D10, D50, D90), critical for dissolution and handling properties. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 148–152°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.