China Factory Direct
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| CAS number | 497-25-6 |
| Product name | 2-Oxazolidone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antiviral agents, antibiotics, and central nervous system drugs | Participates in cycloaddition or condensation reactions with aldehydes, ketones, or isocyanates to construct heterocyclic structures |
| Agrochemicals | Used as a synthetic intermediate for insecticides and fungicides | Alkylated with alkyl halides under basic conditions or acylated with acid chlorides to generate active derivatives |
| Polymers | Used as an epoxy resin curing agent and polyurethane modifier | Undergoes ring-opening reaction with epoxy groups or reacts with isocyanates to introduce flexible segments, thereby enhancing material toughness |
| Organic Synthesis | Used as a versatile synthon for constructing nitrogen-containing heterocyclic compounds | Undergoes alkylation, acylation, or Michael addition via its N–H and C=O functional groups |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Assay | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase C18 column with a mobile phase of water-methanol or water-acetonitrile under gradient elution. Detection is performed using a UV detector at 210–230 nm to quantitatively analyze the purity and content of 2-oxazolidinone. |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | After appropriate derivatization, samples are injected and separated by gas chromatography; mass spectrometry is used for qualitative identification of organic impurities and residual solvents, suitable for detecting volatile impurities. |
| Residual Solvents | Headspace Sampling-Gas Chromatography (HS-GC) | According to ICH guidelines, detects organic solvents potentially residual during production, such as methanol, ethanol, and dichloromethane, using an FID detector for quantification. |
| Water Content | Karl Fischer Titration | Based on the reaction of iodine and sulfur dioxide with water in an anhydrous environment, this method precisely measures water content in samples, suitable for 2-oxazolidinone products sensitive to moisture. |
| Crystalline Form and Crystallinity | X-ray Powder Diffraction (XRD) | Analyzes the crystal structure of solid samples to determine the presence of polymorphism, used to control consistency and stability of active pharmaceutical ingredients. |
| Melting Point | Melting Point Determination | Measures the melting temperature of 2-oxazolidinone using a melting point apparatus or capillary method, serving as a physical property identifier and preliminary purity assessment. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirms the chemical structure and substitution positions of the target compound using ¹H-NMR and ¹³C-NMR spectroscopy. |
| Ultraviolet Absorption Characteristics | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Scans absorbance in the 200–400 nm wavelength range to determine the maximum absorption wavelength (λmax), used for qualitative analysis and auxiliary content determination. |
| Microbial Limits | Microbial Limit Test | Performs aerobic bacterial, mold, and yeast counts, as well as controlled organism tests (e.g., Escherichia coli), in accordance with pharmacopoeial requirements to ensure microbial safety of non-sterile products. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detects heavy metal residues such as lead, cadmium, and mercury to ensure compliance with safety limits for pharmaceutical raw materials. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 48–52°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.