China Factory Direct
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| CAS number | 497-76-7 |
| Product name | Arbutin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Skin-lightening agent | Used as a tyrosinase inhibitor |
| Pharmaceuticals | Antimicrobial agent | Interferes with bacterial metabolism |
| Food | Food preservative | Inhibits microbial growth |
| Personal care & cosmetics | Active ingredient in skin-lightening cosmetics | Formulated into emulsions and serums |
| Biochemistry | Enzyme activity studies | Applied in mechanistic studies of glycosidases |
| Agriculture | Plant metabolism research | Employed in studies of plant secondary metabolism |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Determination of Arbutic Acid Content | High-Performance Liquid Chromatography (HPLC) | A reversed-phase C18 chromatographic column is used with methanol-water or acetonitrile-water as the mobile phase. Detection is performed using a UV detector at wavelengths of 270–280 nm. This method offers high sensitivity and good separation, making it the most commonly used quantitative analysis method. |
| Purity Analysis | Gas Chromatography (GC) | Suitable for analyzing volatile derivatives; arbutic acid must be derivatized (e.g., acetylated) before detection. It is mainly used for trace impurity analysis but involves complex operations and is less frequently applied. |
| Impurity Check (e.g., Hydroquinone) | HPLC-DAD (Diode Array Detection) | While detecting arbutic acid, potential degradation products such as hydroquinone can also be identified and quantified. The characteristic absorption spectra help distinguish impurity peaks to ensure product safety. |
| Structure Identification | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H-NMR and ¹³C-NMR are used to confirm the molecular structure of arbutic acid, especially for identifying isomers or synthetic intermediates. It is an important tool for confirmatory analysis. |
| Molecular Weight Determination | Liquid Chromatography-Mass Spectrometry Coupling (LC-MS) | Accurately determines the molecular weight of arbutic acid and its related impurities, providing fragmentation information for structural analysis and unknown impurity identification. It is highly sensitive and suitable for complex matrix analysis. |
| Content Determination (Rapid Screening) | UV-Visible Spectrophotometry (UV-Vis) | Quantification is based on the characteristic absorption of arbutic acid at 270–280 nm. It is simple to operate and low-cost, but easily affected by coexisting substances. It is only suitable for rough screening or preliminary evaluation. |
| Crystal Form and Water of Crystallization Analysis | X-ray Diffraction (XRD) | Used to analyze the crystal structure of arbutic acid and whether crystalline water is present. It is significant for the stability, solubility, and formulation performance of active pharmaceutical ingredients. |
| Thermal Analysis | Differential Scanning Calorimetry (DSC) | Measures thermal effects during heating to determine the melting point, crystalline state, and possible decomposition of arbutic acid, aiding in quality control. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 199.0 to 203.0 °C |
| Optical Rotation | -68.0 to -63.0 ° (c=1, in water) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.