4-(4-Chlorophenyl)cyclohexanecarboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 49708-81-8 |
| Product name | 4-(4-Chlorophenyl)cyclohexanecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-(4-Chlorophenyl)cyclohexanecarboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-(4-Chlorophenyl)cyclohexanecarboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-(4-Chlorophenyl)cyclohexanecarboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antihistamine drugs (e.g., chlorcyclizine) | Integrated into the target molecular scaffold via acylation, reduction, or coupling reactions |
| Pesticides | Structural building block for insecticidal or herbicidal active ingredients | Condensed with heterocycles or halogenated arenes to construct biologically active molecules |
| Organic Synthesis | Functional intermediate for constructing cyclohexanecarboxylic acid-based structures | Derivatized into complex compounds through esterification, Grignard reactions, or decarboxylation |
Manufacturing Quality Control of 4-(4-Chlorophenyl)cyclohexanecarboxylic acid
| Test Item | Common Test Methods | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Inspect the sample by eye for color, physical state (e.g., white or off-white crystalline powder), and presence of foreign matter to determine compliance with quality specifications. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
IR: Measure the infrared absorption spectrum of the sample and compare it with a reference spectrum; HPLC: Confirm identity by matching retention time with that of a reference standard under specified chromatographic conditions; ¹H NMR: Analyze characteristic chemical shifts and peak patterns to verify molecular structure. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an appropriate mobile phase (e.g., methanol-water or acetonitrile-water system) under isocratic or gradient elution. Detect using a UV detector (typically at 220–254 nm) and calculate the active ingredient content by external standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employ a high-sensitivity HPLC system to separate the main peak from potential impurity peaks (e.g., starting materials, intermediates, degradation products) under optimized chromatographic conditions. Quantify impurities using area normalization or a main component self-reference method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection, a polar capillary column such as DB-624, and FID detection. Perform qualitative and quantitative analysis of organic solvents potentially remaining from synthesis (e.g., toluene, dichloromethane, ethanol) in accordance with ICH Q3C guidelines. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Atmospheric Drying | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, then calculate the percentage weight loss to assess moisture and volatile content. |
| Sulfated Ash (Residue on Ignition) | High-Temperature Ignition Method | Char the sample and then ignite in a furnace at 700–800°C. Weigh the residual inorganic material to estimate total inorganic impurities. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Digest the sample and determine the levels of heavy metal elements such as lead, cadmium, mercury, and arsenic using AAS or ICP-MS to ensure compliance with pharmacopoeial or ICH Q3D limits. |
| pH Value (if in solution) | pH Meter Method | Prepare a solution of defined concentration in water or suitable solvent and measure its acidity or alkalinity using a calibrated pH meter to reflect free acid or impurity levels. |
Technical Specifications of 4-(4-Chlorophenyl)cyclohexanecarboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 148–152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-(4-Chlorophenyl)cyclohexanecarboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-(4-Chlorophenyl)cyclohexanecarboxylic acid
Safety Information of 4-(4-Chlorophenyl)cyclohexanecarboxylic acid
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-(4-Chlorophenyl)cyclohexanecarboxylic acid
Industrial 4-(4-Chlorophenyl)cyclohexanecarboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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