4'-Bromobutyrophenone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4981-64-0 |
| Product name | 4'-Bromobutyrophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4'-Bromobutyrophenone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4'-Bromobutyrophenone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4'-Bromobutyrophenone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing anti-inflammatory drugs, neuroprotective agents, and other pharmaceuticals | Prepared via Friedel–Crafts alkylation of bromoacetophenone with a butylating agent |
| Chemicals | Organic synthesis intermediate for constructing acetophenone derivatives | Obtained by addition of Grignard or organolithium reagents to 4′-bromoacetophenone, followed by hydrolysis |
| Pesticides | Structural building block for synthesizing novel insecticides or fungicides | Used as the aromatic ring component in nucleophilic substitution or coupling reactions to construct active molecular frameworks |
Manufacturing Quality Control of 4'-Bromobutyrophenone
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity (Content) | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, and ultraviolet detection (UV, 254 nm). Quantification is performed using external standard or internal standard methods, enabling accurate determination of main component content. This is the most commonly used method for purity assessment. |
| Impurity Analysis | High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) | Combines the separation capability of HPLC with the qualitative and quantitative power of MS, allowing identification and quantification of trace impurities (e.g., synthetic by-products, degradation products). Suitable for structural elucidation and impurity profiling. |
| Structural Elucidation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide detailed molecular structure information, confirming the position of bromine substitution and carbonyl groups. Considered the gold standard for compound structure confirmation. |
| Molecular Weight Confirmation | Mass Spectrometry (MS) | Utilizes electron ionization (EI) or electrospray ionization (ESI) sources to obtain molecular ion peaks ([M]⁺), verifying whether the measured molecular weight matches the theoretical value (e.g., calculated molecular formula C₈H₇BrO, molecular weight approximately 167.0). |
| Melting Point Determination | Micro Melting Point Apparatus Method | Determines the melting range by observing the sample's melting behavior during heating, serving as a preliminary method to assess purity and identity. Pure substances typically exhibit a narrow melting range (e.g., 135–137°C). |
| Residual Solvent Testing | Gas Chromatography (GC) | Employs capillary columns (e.g., DB-624 or similar polar columns), with headspace or direct injection, to detect organic solvents potentially remaining from reactions (e.g., ethanol, dichloromethane, acetone), meeting ICH Q3C requirements. |
| Water Content | Karl Fischer Titration (KF) | Uses coulometric or volumetric Karl Fischer reagent to accurately determine water content in samples, commonly applied to assess the dryness level of raw materials or intermediates. |
| Bromine Element Content | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Energy Dispersive X-ray Fluorescence (EDXRF) | Used for quantitative analysis of bromine content, verifying whether bromine substitution conforms to stoichiometry, particularly suitable for complex matrices or scenarios requiring elemental-level analysis. |
Technical Specifications of 4'-Bromobutyrophenone
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 52.0–56.0°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4'-Bromobutyrophenone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4'-Bromobutyrophenone
Packaging of 4'-Bromobutyrophenone
Industrial 4'-Bromobutyrophenone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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