China Factory Direct
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| CAS number | 49844-90-8 |
| Product name | 4-Chloro-2-methylthiopyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for fungicide synthesis | Prepared via chlorination and methylthio substitution on the pyrimidine ring |
| Pharmaceuticals | Intermediate for antiviral and anticancer drug synthesis | Used as a pyrimidine scaffold to construct bioactive molecules |
| High-performance polymers | Organic synthesis intermediate for functional material development | Employed to prepare polymer monomers with tailored electrical properties or thermal stability |
| Fine chemicals | Intermediate for dye and functional additive synthesis | Functional groups introduced via coupling, acylation, and related reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; individual impurities reported relative to main peak using external standard or area normalization. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, toluene) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Chloride Content | Ion Chromatography (IC) | Separation of chloride anion on an anion-exchange column with conductivity detection, quantified against chloride standards. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using plasma emission spectroscopy. |
| Sulfur Content (as thioether) | Combustion IC | Oxidative combustion followed by ion chromatographic detection of sulfate; calculates total sulfur from thioether functionality. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range at which solid-to-liquid phase change occurs. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against standard reference. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile residue remaining after high-temperature ashing at 700-800 C, expressed as percentage of original sample. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode after equilibration. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity vs. angle to determine volume-based particle size distribution in dispersed sample. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 45–49°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.