2,4-Dichloro-5-nitropyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 49845-33-2 |
| Product name | 2,4-Dichloro-5-nitropyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4-Dichloro-5-nitropyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4-Dichloro-5-nitropyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4-Dichloro-5-nitropyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of herbicide intermediates | Preparation of 2,4-dichloro-5-nitropyrimidine via chlorination and nitration, for synthesis of novel pyrimidine-based herbicides |
| Pharmaceuticals | Drug synthesis intermediate | Used as a pyrimidine ring precursor in the synthesis of antibacterial or antiviral agents, participating in multistep organic synthesis |
| Polymers | Functional monomer additive | Applied to modify polymer materials to enhance thermal stability and flame retardancy |
| Dyes | Dye intermediate | Used in the synthesis of nitrogen-containing heterocyclic dyes to improve color fastness and lightfastness |
Manufacturing Quality Control of 2,4-Dichloro-5-nitropyrimidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, based on peak area comparison against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and detection of structurally related impurities (e.g., mono-chloro, nitro-reduced, hydrolyzed derivatives) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., dichloromethane, toluene, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals | ICP-MS or AAS (after acid digestion) | Quantification of toxic elements (e.g., Pb, Cd, As, Hg) following microwave-assisted nitric/hydrogen peroxide digestion and elemental analysis. |
| Chloride Ion Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation and quantification of free chloride ions using anion-exchange column and suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-phase transition temperature range using controlled heating and optical observation of sample liquefaction. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of inorganic residue after high-temperature (700–800 °C) ashing of sample in platinum crucible. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution by measuring angular scattering intensity of laser light passing through dispersed sample. |
| Bulk & Tapped Density | ASTM D6393 (Tap Density Tester) | Determination of bulk density (loose) and tapped density via standardized mechanical tapping of a known mass in a graduated cylinder. |
| Organic Volatile Impurities (e.g., Nitrobenzene, Chlorobenzene) | GC-MS | Targeted screening and quantification of genotoxic impurities using gas chromatography coupled with mass spectrometry and isotope-labeled internal standards. |
| pH of Aqueous Suspension | pH Meter (10% w/v suspension in water) | Measurement of hydrogen ion activity in a standardized aqueous suspension using calibrated pH electrode. |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic residue after charring and sulfuric acid treatment followed by incineration at 600–700 °C. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to detect chiral impurities or enantiomeric contamination (if applicable; typically negligible but verified). |
Technical Specifications of 2,4-Dichloro-5-nitropyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Yellow crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124.0–127.0 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4-Dichloro-5-nitropyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4-Dichloro-5-nitropyrimidine
Safety Information of 2,4-Dichloro-5-nitropyrimidine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,4-Dichloro-5-nitropyrimidine
Industrial 2,4-Dichloro-5-nitropyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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