DL-Histidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4998-57-6 |
| Product name | DL-Histidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for DL-Histidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk DL-Histidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of DL-Histidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of anti-ulcer drugs (e.g., cimetidine) | Chemical synthesis |
| Food | Nutritional fortificant to supplement essential amino acids in human diets | Formulation addition |
| Animal Feed | Added to animal feed to improve protein nutritional balance | Blending and pelleting |
| Cosmetics | Humectant and skin-conditioning agent | Formulation compounding |
| Biotechnology | Component of cell culture media to support microbial or mammalian cell growth | Media preparation |
| Analytical Chemistry | Buffer or chelating agent in metal ion analysis | Solution preparation |
Manufacturing Quality Control of DL-Histidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (DL-Histidine Content) | Acid-Base Titration | Quantifies main component via titration with standardized HCl solution using bromocresol green indicator. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral DL-histidine in solution at specified concentration and wavelength. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Determines hydrogen ion activity using calibrated pH electrode in a 1% w/v aqueous solution. |
| Loss on Drying | Gravimetric (Thermogravimetry) | Determines volatile matter content by measuring mass loss after drying at 105 C for 2 hours. |
| Residue on Ignition | Gravimetric (Sulfated Ash) | Measures non-volatile inorganic impurities after ignition at 600-700 C following sulfuric acid treatment. |
| Heavy Metals (as Pb) | Colorimetric (Thiourea Method) | Compares intensity of colored complex formed with thiourea under acidic conditions against lead standard. |
| Iron (Fe) | Atomic Absorption Spectroscopy (AAS) | Quantifies iron by measuring absorption of specific UV-Vis radiation by ground-state Fe atoms in flame. |
| Sulfate (SO4) | Turbidimetric Method | Measures sulfate as barium sulfate precipitate turbidity in acidic medium using barium chloride reagent. |
| Chloride (Cl) | Argentometric Titration (Mohr Method) | Titration with standardized silver nitrate using potassium chromate indicator to detect endpoint by red Ag2CrO4 formation. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) | Separates and quantifies structurally similar impurities using reversed-phase C18 column and UV detection. |
| Microbial Limits | Membrane Filtration / Plate Count | Determines total aerobic microbial count and absence of specified pathogens via filtration, incubation, and colony enumeration. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution by measuring angular variation in intensity of laser light scattered by dispersed sample. |
Technical Specifications of DL-Histidine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 265-275°C (decomposes) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of DL-Histidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of DL-Histidine
Packaging of DL-Histidine
Industrial DL-Histidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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