China Factory Direct
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| CAS number | 5000-66-8 |
| Product name | 2-Bromo-2'-chloroacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthesis of antidepressant drugs | Used as an intermediate in aromatic compound synthesis reactions |
| Pesticide Industry | Synthesis of insecticides or herbicides | Applied in chlorination or bromination reactions to generate biologically active compounds |
| Chemical Reagents | Laboratory research | Employed in halogenation reactions during organic synthesis experiments |
| Materials Science | Preparation of specialty functional materials | Incorporated as a functional group into polymers or other materials |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Measures the infrared absorption spectrum of the sample and compares it with the reference spectrum to confirm the presence of characteristic functional groups of 2-bromo-2'-chloroacetophenone, such as carbonyl (C=O), aromatic ring, C–Br, and C–Cl absorption peaks. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Utilizes ¹H NMR to analyze chemical shifts, integration areas, and coupling constants of hydrogen atoms, verifying structural features such as aromatic protons and methyl protons to ensure they match expected signals. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water as mobile phase, detected by UV detector (typically around 254 nm). The main component content is determined using external standard or internal standard method, offering high sensitivity and good reproducibility. |
| Gas Chromatography (GC) (for samples with good volatility) | If the sample has good thermal stability and moderate volatility, GC-FID or GC-MS can be used for quantitative analysis; however, caution is required due to potential decomposition at elevated temperatures. | |
| Related Substances / Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Employs gradient or isocratic elution programs to separate the main peak from potential impurities (e.g., unreacted raw materials, by-products, degradation products). Impurity levels are controlled using area normalization or reference standard methods. |
| Moisture Content Determination | Karl Fischer Titration | Uses either volumetric or coulometric Karl Fischer titration to determine water content, suitable for quality control of moisture-sensitive organic compounds. |
| Melting Point Determination | Capillary Melting Point Method | Determines the melting range of the sample and compares it with literature values (approximately 70–73 °C) as an auxiliary indicator for purity and identity confirmation. |
| Residual Solvents | Gas Chromatography (Headspace GC) | Follows ICH Q3C guidelines; uses headspace-GC-FID or GC-MS to detect residual organic solvents (e.g., dichloromethane, toluene, ethanol) potentially present from manufacturing processes. |
| Heavy Metals / Elemental Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Performs testing for harmful elements such as lead, cadmium, mercury, and arsenic according to ICH Q3D guidelines to ensure compliance with safety limits. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow Liquid |
| ldentification(NMR) | Conforms to structure |
| Purity | ≥95.0% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.