2,4-Morpholinedicarboxylic acid, 4-(1,1-diMethylethyl) 2-Methyl ester Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 500789-41-3 |
| Product name | 2,4-Morpholinedicarboxylic acid, 4-(1,1-diMethylethyl) 2-Methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 500789-41-3
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 500789-41-3 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 500789-41-3
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key intermediate for synthesizing targeted anticancer drugs containing a morpholine ring (e.g., PI3K/mTOR inhibitors) | Introduction of specific aryl/heteroaryl moieties via palladium-catalyzed cross-coupling or aminolysis under inert atmosphere, followed by BOC deprotection |
| Pharmaceutical R&D | Building block for constructing protein kinase inhibitor scaffolds bearing a 2-morpholinoacetyl side chain | Amidation with amine substrates, followed by selective BOC deprotection under acidic conditions (e.g., HCl/dioxane) |
| Fine Chemicals | Standard precursor for synthesizing chiral morpholine derivatives used to prepare optically pure pharmaceutical intermediates | After obtaining a single enantiomer via enzymatic kinetic resolution or chiral chromatographic separation, employed in subsequent cyclization or substitution reactions |
Manufacturing Quality Control of 500789-41-3
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., N-BOC-2-aminomorpholine, hydrolysis products) via gradient HPLC separation and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, methanol, toluene) using capillary GC with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration based on iodine consumption in pyridine/methanol buffer. |
| Acid Value | Acid-Base Titration | Measures free acid content via titration with standardized NaOH solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Quantifies non-volatile inorganic residue after high-temperature ashing and weighing. |
| Heavy Metals | ICP-OES | Simultaneously detects trace metals (e.g., Pb, Cd, Ni, Fe) by atomic emission spectroscopy after acid digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation using sodium D-line light in a polarimeter to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating purity and identity. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in suspension using Mie scattering theory and laser diffraction optics. |
| Microbial Limits | Membrane Filtration | Detects aerobic bacteria, yeast, and mold by filtration, membrane transfer to selective media, and colony enumeration. |
Technical Specifications of 500789-41-3
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | 62–66°C |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 500789-41-3
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 500789-41-3
Packaging of 500789-41-3
Industrial 500789-41-3 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply