4,6-Dichloro-5-methoxypyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5018-38-2 |
| Product name | 4,6-Dichloro-5-methoxypyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,6-Dichloro-5-methoxypyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,6-Dichloro-5-methoxypyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,6-Dichloro-5-methoxypyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for herbicides, used in the synthesis of sulfonylurea herbicides such as nicosulfuron | Used in multi-step reactions—including condensation and sulfonylation—with 2-amino-4,6-dimethoxypyrimidine to prepare nicosulfuron |
| Pharmaceuticals | Intermediate for antimicrobial agents, used in the synthesis of dihydrofolate reductase inhibitors | Participates in cyclization and substitution reactions to construct pyrimidine-based antimicrobial scaffolds, e.g., in the synthesis of certain broad-spectrum antimicrobial lead compounds |
| Organic Synthesis | Building block for heterocyclic compound synthesis | Serves as a chloro- and methoxy-substituted pyrimidine core for functionalized pyrimidine derivative synthesis via Suzuki coupling, nucleophilic substitution, and related transformations |
Manufacturing Quality Control of 4,6-Dichloro-5-methoxypyrimidine
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection | Observe the color, physical state, and visible impurities of the sample. Typically appears as a white to off-white crystalline powder. |
| Melting Point | Capillary Melting Point Determination | Determine the melting temperature range using a melting point apparatus, used to assess purity and substance consistency. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Utilize reversed-phase HPLC (e.g., C18 column) with UV detection (around 254 nm), employing external standard or internal standard method for quantitative analysis of the main component. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate degradation products or synthetic intermediates via gradient or isocratic elution, detect and quantify individual impurity peaks to evaluate purity. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or solution injection to detect residual organic solvents (e.g., methanol, ethanol, acetone) from manufacturing processes. |
| Water Content | Karl Fischer Titration | Accurately determine moisture content via titration, suitable for moisture-sensitive organic compounds. |
| Heavy Metals | Sulfide Colorimetry or ICP-MS | Colorimetric method for limit testing; ICP-MS enables precise quantification of heavy metal residues such as lead, cadmium, and mercury. |
| Chlorine Content (Elemental Analysis) | Oxygen Flask Combustion - Ion Chromatography | After combustion of the sample in an oxygen flask, released chloride ions are determined by ion chromatography to verify chlorine content matches theoretical value. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS), Infrared Spectroscopy (IR) | Comprehensive use of ¹H-NMR, ¹³C-NMR, ESI-MS or EI-MS, and FT-IR to confirm molecular structure consistency with the target compound. |
Technical Specifications of 4,6-Dichloro-5-methoxypyrimidine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,6-Dichloro-5-methoxypyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,6-Dichloro-5-methoxypyrimidine
Safety Information of 4,6-Dichloro-5-methoxypyrimidine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4,6-Dichloro-5-methoxypyrimidine
Industrial 4,6-Dichloro-5-methoxypyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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