3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 503615-03-0 |
| Product name | 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Intermediate for sildenafil analogues | Serves as a key structural unit in the chemical synthesis of pyridone ring structures found in PDE5 inhibitor drug molecules. |
| Pharmaceutical Chemicals | Drug discovery and development | Used as a candidate compound or reference standard for PDE5 (phosphodiesterase type 5) inhibitors in biological activity testing and screening. |
| Research Reagents | Organic synthesis research | Applied in methodology studies for synthesizing pyridone derivatives containing morpholino and nitrophenyl groups, and in characterizing their physicochemical properties. |
Manufacturing Quality Control of 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at characteristic wavelength, calibrated against reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV, with identification and reporting relative to main peak. |
| Residual Solvents | GC-FID | Detection and quantification of organic solvents by gas chromatography with flame ionization detection, per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in sample. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and dilution. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by weighing of residual inorganic ash after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, indicating purity and identity. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in suspension using Mie scattering theory and laser diffraction optics. |
| Bulk Density | USP <616> Tap Density Test | Measurement of mass per unit volume before and after mechanical tapping to assess powder flow properties. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and detection of specified pathogens using selective culture media and incubation. |
Technical Specifications of 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 178–182 °C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
Safety Information of 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
Industrial 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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