China Factory Direct
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| CAS number | 504-30-3 |
| Product name | 3(2H)-Pyridazinone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pyridazinone heterocyclic compounds or pharmaceutical intermediates | Functionalization reactions (e.g., halogenation, alkylation) performed on the 3-pyridazinone core |
| Pharmaceuticals | Production of cardiovascular drugs (e.g., antihypertensives) | Serving as a key intermediate in constructing molecular scaffolds with specific pharmacological activity |
| Pharmaceuticals | Development of antiviral or antibacterial agents | Incorporation of the pyridazinone moiety via cyclization or condensation reactions to enhance drug activity |
| Chemicals | Organic synthesis intermediate | Used in constructing nitrogen-containing heterocycles and participating in C–C or C–N bond-forming reactions |
| Test Item | Common Testing Method | Method Overview |
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| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white crystalline powder), and check for impurities or foreign particles. |
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with water-methanol or water-acetonitrile as the mobile phase, detect the main peak at approximately 254 nm using a UV detector, and calculate purity or content via external standard or normalization method. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Utilize ¹H-NMR and ¹³C-NMR to analyze hydrogen and carbon skeletal structures, confirming whether the compound matches the characteristic peaks of 3-pyridinone. |
| Structural Confirmation | Mass Spectrometry (MS) | Employ ESI or EI ionization to obtain molecular ion peaks ([M+H]+ or M⁺), verifying that the molecular weight matches the target compound. |
| Water Content | Karl Fischer Titration | Quantitatively determine moisture content in samples through electrochemical reaction; suitable for controlling residual moisture in active pharmaceutical ingredients. |
| Residual Solvents | Gas Chromatography (GC) | Use capillary columns with FID detection to detect common residual solvents such as methanol, ethanol, acetone, and dichloromethane according to ICH guidelines. |
| Melting Point | Melting Point Determination | Determine the melting temperature range using a melting point apparatus or capillary tube method to assess crystallinity and purity (pure substances typically exhibit sharp melting points). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measure levels of heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeial or relevant safety standards. |
| Related Substances (Impurities) | HPLC Method | Separate the main component from impurity peaks under gradient or isocratic conditions, detect and quantify degradation products or synthesis-related intermediates to evaluate product stability and process purity. |
| Polymorph Analysis | X-Ray Diffraction (XRD) | Analyze the crystal structure of solid samples to identify different polymorphic forms, ensuring batch-to-batch consistency—particularly critical in formulation development. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.