China Factory Direct
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| CAS number | 5053-43-0 |
| Product name | 2-Methylpyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 5L/bottle25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for antiviral and anticancer drug development | Used as a pyrimidine scaffold in multistep organic synthesis reactions |
| Agrochemicals | Intermediate for pesticide development, including novel herbicides and insecticides | Applied in nucleophilic substitution or cyclization reactions to construct complex molecular structures |
| Polymers & Materials | Monomer or modifier for functional polymeric materials | Integrated into polymer chains via polymerization to introduce side chains and enhance material properties |
| Organic Synthesis | General-purpose reagent for synthesizing nitrogen-containing heterocyclic compounds | Employed in coupling or cycloaddition reactions under catalytic conditions |
| Test Item | Common Testing Methods | Method Overview |
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| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column and UV detector (e.g., 254 nm), with methanol/water or acetonitrile/buffer salt as mobile phase, to quantify the purity of the main component and separate impurity peaks. Suitable for accurate determination of samples with purity ≥98%. |
| Impurity Content | HPLC or GC-MS | HPLC is used for non-volatile impurities; GC-MS is suitable for qualitative and semi-quantitative analysis of volatile organic impurities, identifying unknown impurity structures by matching with mass spectral libraries. |
| Moisture Content | Karl Fischer Titration | Based on electrochemical titration principle, where iodine reacts with sulfur dioxide in a pyridine/methanol system with water, enabling precise measurement of trace moisture in samples (typically required ≤0.5%). |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Residual solvents are released by heating the sample, separated on a capillary column, and quantified using FID or MS detectors. Commonly used to detect process-related residual solvents such as methanol, ethanol, and ethyl acetate. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirms molecular structural integrity through analysis of characteristic chemical shifts and coupling constants in 1H NMR and 13C NMR spectra, ruling out interference from isomers or by-products. |
| Melting Point | Capillary Melting Point Apparatus | Determines the temperature at which a substance transitions from solid to liquid using a digital melting point apparatus (theoretical melting point of 2-methylpyrimidine is approximately 38–40°C) to assess crystalline purity and thermal stability. |
| Appearance and Color | Visual Comparison / Colorimeter | Visually inspect under standard lighting conditions for colorless to pale yellow liquid or crystals; alternatively, use a colorimeter to measure Lab* values for consistent control of product appearance. |
| pH Value (aqueous solution) | pH Meter Measurement | Prepare an aqueous solution of defined concentration and measure its acidity/basicity using a calibrated pH meter (2-methylpyrimidine is weakly basic, pH ≈ 8–9), to evaluate presence of acidic impurities. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After microwave digestion of the sample, ICP-MS simultaneously detects residual levels of elements such as Pb, As, Cd, and Hg, ensuring compliance with ICH Q3D limits (typically ≤10–20 ppm). |
| Test Item | Specification |
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| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.505–1.515 |
| Relative Density (20°C/25°C) | 1.025–1.045 g/cm³ |
| Odor | Characteristic pyrimidinic odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.