4-Amino-1-benzylpiperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 50541-93-0 |
| Product name | 4-Amino-1-benzylpiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Amino-1-benzylpiperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Amino-1-benzylpiperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Amino-1-benzylpiperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of opioid analgesics (e.g., tapentadol) | Produced via ammonolysis with 4-chloro-1-benzylpiperidine or via reductive amination of 4-oxo-1-benzylpiperidine |
| Pharmaceutical Intermediates | Building block for molecular scaffolds of selective 5-HT1A receptor agonists and neuroprotective agents | Serves as a chiral piperidine heterocyclic unit in subsequent functional group transformations, including coupling, alkylation, and asymmetric catalytic modifications |
| Organic Synthesis | Structural module for highly selective phase-transfer catalysts | Coordinated with chiral acids or metal complexes for asymmetric alkylation or epoxidation reactions |
Manufacturing Quality Control of 4-Amino-1-benzylpiperidine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) Nuclear Magnetic Resonance Proton Spectrum (¹H NMR) High-Performance Liquid Chromatography (HPLC) |
Confirm structural consistency by comparing characteristic IR absorption peaks, ¹H NMR chemical shifts and coupling constants, or HPLC retention times with those of reference standards. |
| Assay | High-Performance Liquid Chromatography (HPLC) Gas Chromatography (GC) |
Quantitative determination of the main component using reversed-phase HPLC or GC with appropriate columns and mobile phase/carrier gas systems. External standard or internal standard methods are applied to ensure content meets specified limits (typically ≥98.0%). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use gradient or isocratic HPLC to separate and detect potential organic impurities (e.g., starting materials, intermediates, by-products, degradation products). Individual impurity levels are calculated using area normalization or correction factor methods. |
| Residual Solvents | Gas Chromatography (GC, Headspace Injection) | According to ICH Q3C guidelines, residual organic solvents from synthesis or purification processes (such as methanol, dichloromethane, ethanol, toluene, etc.) are detected using headspace gas chromatography. Limits comply with pharmacopoeial requirements. |
| Water Content | Karl Fischer Titration | Accurately determine moisture content using volumetric or coulometric Karl Fischer titration, ensuring levels remain within specified limits (typically ≤0.5%). |
| Melting Point | Capillary Melting Point Method | Determine the melting temperature range using a melting point apparatus; used as a physical constant for identification and purity assessment. |
| Appearance | Visual Inspection | Observe color and physical state (e.g., white to off-white crystalline powder), which should conform to standard descriptions. |
| pH Value (if prepared as solution) | pH Meter Method | Dissolve the sample into an aqueous solution of defined concentration and measure pH using a calibrated pH meter to assess whether acidity or alkalinity meets specifications. |
Technical Specifications of 4-Amino-1-benzylpiperidine
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.5% (HPLC) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | -20°C to -15°C |
| Identification (NMR) | Conforms to reference standard |
| Odor | Characteristic mild amine odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Amino-1-benzylpiperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Amino-1-benzylpiperidine
Packaging of 4-Amino-1-benzylpiperidine
Industrial 4-Amino-1-benzylpiperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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