China Factory Direct
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| CAS number | 50573-74-5 |
| Product name | 2-Amino-6-nitrobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate | Used in the synthesis of certain pharmaceuticals, including anti-inflammatory agents and antibiotic intermediates |
| Dye Industry | Intermediate | Applied in the production of specific dye intermediates |
| Pesticide Industry | Intermediate | Used in the synthesis of active ingredients in pesticides |
| Research Institutions | Laboratory Research | Employed in laboratory studies of chemical reactions to develop novel compound synthesis methods |
| Biochemistry | Research on Biologically Active Substances | Serves as a raw material or reagent for studying biologically active substances and their mechanisms of action in biological systems |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection + Physical Property Measurement | Observe the sample's color (usually a yellow to orange-yellow crystalline powder), crystal form, solubility (slightly soluble in water, easily soluble in ethanol, ether, and alkaline solutions), etc. |
| Melting Point | Capillary Melting Point Apparatus Method | Determined according to the Chinese Pharmacopoeia or USP method, the melting point of 2-aminobenzoic acid is approximately 268–272 °C, used for preliminary purity assessment. |
| Content Determination (Main Component) | High-Performance Liquid Chromatography (HPLC) | Use a C18 chromatographic column, with a mobile phase of methanol-water (with 0.1% formic acid or phosphate buffer), detected by ultraviolet detector (wavelength 254–280 nm), external standard method for quantification, high accuracy, suitable for quantitative analysis. |
| Content Determination (Main Component) | UV-Vis Spectrophotometry | Determine absorbance at maximum absorption wavelength (approximately 270–280 nm), calculate content through standard curve, suitable for rapid screening, but prone to interference from impurities. |
| Impurity Analysis | High-Performance Liquid Chromatography (HPLC) | Use gradient elution or isocratic elution, detect possible impurities such as 2-nitrobenzoic acid, 2,6-dinitrobenzoic acid, unreacted raw materials, etc., calculate total impurities and individual impurity limits. |
| Moisture Content | Karl Fischer Titration | Accurately determine the trace moisture content in the sample, control the impact of moisture on stability, typically requiring moisture ≤1.0%. |
| Inorganic Impurities such as Chlorides and Sulfates | Turbidimetry / Ion Chromatography | Process the sample according to pharmacopoeia methods, determine chloride or sulfate ion content by turbidimetry, or perform quantitative analysis using ion chromatography. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or ICP-MS | Determine the content of heavy metals such as lead, cadmium, mercury, and arsenic after ashing or digestion of the sample, complying with ICH Q3D or pharmacopoeia limits (e.g., ≤20 ppm). |
| Particle Size Distribution (if applicable) | Laser Diffraction or Microscopy | For powder formulation raw materials, measure the particle size distribution to ensure process consistency, especially affecting dissolution and homogeneity in formulations. |
| Solvent Residues | Gas Chromatography (GC) | Detect residual organic solvents (such as methanol, ethanol, acetone, ethyl acetate) during production, controlled within limits according to ICH Q3C standards. |
| pH Value (in Aqueous Solution) | pH Meter Method | Prepare a saturated aqueous solution (or appropriate concentration), measure pH with a calibrated pH meter. The aqueous solution of 2-aminobenzoic acid is weakly acidic (pH ≈ 4–6), reflecting the state of acidic groups. |
| Identification Test | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare characteristic absorption peaks with standard spectra (e.g., carboxyl group C=O stretching vibration ~1680 cm⁻¹, amino N-H ~3400 cm⁻¹, nitro NO₂ ~1530, 1350 cm⁻¹) to confirm the structure. |
| Identification Test | Thin-Layer Chromatography (TLC) | Use silica gel plates, develop with an eluent such as ethyl acetate: methanol: glacial acetic acid (8:2:1), visualize with iodine vapor or under UV light, compare Rf values with reference standards. |
| Test Item | Specification |
|---|---|
| Appearance | Light yellow to brown crystalline powder |
| Purity | >=98.0% (HPLC) |
| Melting Point | 175–179°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.