BOC-D-HIS-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 50654-94-9 |
| Product name | BOC-D-HIS-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-D-HIS-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-D-HIS-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-D-HIS-OH
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical intermediates | Used as a chiral building block for the synthesis of peptide-based drugs |
| Chemical synthesis | Protecting agent for peptide synthesis | Applied for temporary protection of the histidine side chain in solid-phase or solution-phase peptide synthesis |
| Biotechnology | Molecular probe synthesis | Used to synthesize specifically labeled peptides or proteins for biological activity studies |
| Diagnostics reagents | Enzyme inhibitor development | Employed to construct specific structures that mimic enzyme substrates for inhibitor screening |
| Materials science | Functional material construction | Incorporated as a structural unit into functional polymers or nanomaterials |
Manufacturing Quality Control of BOC-D-HIS-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase, with quantitation based on relative peak areas. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to react stoichiometrically with water in the sample. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., DMF, THF, EtOAc). |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification by inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-MS | Specific quantification of palladium catalyst residue using isotope-discriminating mass detection after microwave digestion. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity under controlled white light against established reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., deprotected histidine, BOC-anhydride adducts) using gradient HPLC. |
| Loss on Drying | Gravimetric Thermobalance | Mass loss measured after heating under controlled temperature and vacuum or nitrogen purge per USP <731>. |
| pH of Solution | Potentiometric pH Measurement | pH determination of a standardized aqueous solution (e.g., 1% w/v) using calibrated glass electrode and pH meter. |
Technical Specifications of BOC-D-HIS-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -26.0 to -25.0 deg (c=1, 1M HCl) |
| Melting Point | 220 to 225 °C (dec.) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-D-HIS-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-D-HIS-OH
Packaging of BOC-D-HIS-OH
Industrial BOC-D-HIS-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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