China Factory Direct
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| CAS number | 50670-49-0 |
| Product name | 4-Bromo-4'-methylbiphenyl |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Electronic GradeMaterial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Structural building block for synthesizing antitumor agents and selective estrogen receptor modulators (SERMs) | Used as an aryl bromide in palladium-catalyzed cross-coupling reactions, including Suzuki and Heck couplings |
| Organic Optoelectronic Materials | Precursor for hole-transport layers or host materials in organic light-emitting diodes (OLEDs) | Further functionalized via the bromine atom (e.g., amination, cyanation) to construct conjugated fused-ring systems, followed by vacuum deposition or solution-based film formation |
| Liquid Crystal Materials | Rigid biphenyl core component in nematic liquid crystal monomers | Reacted with terminal-group-containing compounds (e.g., cyano- or alkoxy-substituted reagents) via Williamson ether synthesis or nucleophilic cyanide substitution to assemble mesogenic molecules |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., mono-bromo isomers, desbromo, dibromo analogs) relative to main peak area. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., toluene, methanol, THF) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric titration with iodine-based reagent; water reacts stoichiometrically to determine trace moisture content. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion; measures total metal content (Pb, Cd, Hg, As, Cr) against USP <232> limits. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anion using conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 600 C followed by weighing of inorganic residue to assess inorganic impurity load. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically; confirms identity and crystallinity per USP <741>. |
| Appearance | Visual Inspection | Assessment of color and physical state (white to off-white crystalline powder) under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using light scattering to determine D10, D50, D90 values. |
| Bulk Density | ASTM D1895 Method A | Measurement of mass per unit volume for freely settled powder in a graduated cylinder. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of Pd catalyst residue after microwave-assisted digestion, per ICH Q2(R2) sensitivity requirements. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.