China Factory Direct
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| CAS number | 50670-64-9 |
| Product name | 5-AMINO-2-METHYLBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the insecticide flupyradifurone | Used as an aromatic amine precursor in critical coupling or cyclization steps during the multi-step synthesis of flupyradifurone via nitration, reduction, and cyanation |
| Pharmaceuticals | Used to synthesize quinazoline- and benzimidazole-based drug candidates with antitumor and anti-inflammatory activity | Applied in diazotization–iodination, palladium-catalyzed cross-coupling, or cyclization reactions to construct nitrogen-containing heterocyclic scaffolds |
| Dyes | Light- and heat-stable auxochrome intermediate for azo dyes and reactive dyes | Employed in diazotization followed by coupling with phenolic or amine components; the synergistic electronic effect of the cyano and amino groups enhances dye fixation performance |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~220 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., 2-methylbenzonitrile, 5-amino-2-methylbenzoic acid) using gradient elution and spectral confirmation. |
| Moisture Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the reaction of iodine with water in anhydrous methanol/pyridine medium; measures trace water content precisely. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Incineration at 700–800 °C followed by sulfuric acid treatment and weighing of non-volatile inorganic residue. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion, measuring emission intensities of metal-specific wavelengths in plasma. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of chloride ions on anion-exchange column and quantitative detection via suppressed conductivity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance (Color & Clarity) | Visual Inspection against Standard Solutions | Comparison of sample solution (in specified solvent) to platinum-cobalt color standards and assessment of particulate clarity. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined saturated aqueous suspension using a calibrated electrode system. |
| Organic Volatile Impurities (e.g., residual solvents) | GC-FID | Headspace or direct injection GC analysis with flame ionization detection, quantifying common solvents (e.g., toluene, methanol) against internal standard. |
| Bulk Density | ASTM D1895 Method A | Determination of mass per unit volume of freely settled powder in a standardized cylinder. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate volumetric particle size distribution in dispersed powder samples. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity (if applicable; typically low for this compound). |
| Test Item | Specification |
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| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.