China Factory Direct
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| CAS number | 5080-50-2 |
| Product name | O-Acetyl-L-carnitine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Cognitive enhancement, neuroprotection, treatment of Alzheimer’s disease and depression | Chemical synthesis, biological fermentation |
| Dietary Supplements | Enhancement of energy metabolism, support for weight management, anti-fatigue effects | Purification, formulation processing |
| Sports Nutrition | Improvement of exercise endurance, reduction of lactic acid accumulation, promotion of post-exercise recovery | Formulation blending, capsule/tablet manufacturing |
| Food Additives | Functional food ingredient (e.g., in energy drinks) | Dissolution, homogenization |
| Cosmetics | Antioxidant, anti-aging agent (stimulating skin cell metabolism) | Emulsification, microencapsulation |
| Agriculture | Plant growth regulator (enhancing stress tolerance) | Spray drying, coating |
| Test Item | Common Testing Method | Method Overview |
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| Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a reverse-phase C18 column, with methanol-water or phosphate buffer as the mobile phase, and detection by UV detector (200–220 nm). This method accurately determines the content of acetyl-L-carnitine, providing good resolution and high reproducibility. It is currently the most commonly used quantitative method. |
| Purity Analysis | Gas Chromatography (GC) | Suitable for analysis of volatile derivatives. Acetyl-L-carnitine is typically derivatized (e.g., acetylated and methylated), separated using a capillary column, and detected by a flame ionization detector (FID) to evaluate purity and impurities. |
| Impurity Testing | HPLC Method (Impurity Peak Area Normalization) | Using the same chromatographic conditions as the main component, potential synthetic byproducts, degradation products, or isomers (such as L-carnitine, incomplete acetylated products, etc.) are detected. Impurity levels are controlled by setting limit standards. |
| Optical Rotation Measurement | Polarimetry | Acetyl-L-carnitine exhibits optical activity, and its specific rotation should fall within a specified range (e.g., +10° to +14°, at 20°C, D line). This method confirms stereochemical purity and enantiomeric purity. |
| Melting Point Determination | Micro Melting Point Apparatus Method | Determining the melting temperature range (e.g., approximately 170–175°C) helps assess purity. The presence of impurities may broaden the melting range or lower the melting point. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FTIR) | Characteristic absorption peaks (e.g., amide I band ~1650 cm⁻¹, C=O stretching vibration ~1740 cm⁻¹, N–H bending, etc.) are used to confirm molecular structure and verify compound identity. |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR / ¹³C-NMR | Provides detailed structural information, confirming the position of the acetyl group, the configuration of the chiral center, and the presence of isomers or residual solvents. It is one of the gold standard methods for structural confirmation. |
| Residual Solvent Detection | Gas Chromatography-Mass Spectrometry (GC-MS) | Used to detect organic solvents potentially introduced during production (e.g., ethanol, acetone, dichloromethane), complying with ICH Q3A/B requirements to ensure safety. |
| Microbial Limit Test | Microbial Count Method (Aerobic Bacteria, Molds/Yeast) | According to Chinese Pharmacopoeia or USP/EP standards, this method tests microbial contamination levels in the sample to ensure sterility or acceptable microbial load. |
| Heavy Metal Detection | Atomic Absorption Spectrometry (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Determines heavy metal content such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmaceutical safety standards (e.g., ≤10 ppm). |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -29.0 to -27.0 deg (c=1, H2O) |
| Melting Point | 195 to 199 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.