Methyl 2-nitro-3,4,5-trimethoxybenzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5081-42-5 |
| Product name | Methyl 2-nitro-3,4,5-trimethoxybenzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 2-nitro-3,4,5-trimethoxybenzoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 2-nitro-3,4,5-trimethoxybenzoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 2-nitro-3,4,5-trimethoxybenzoate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing antitumor agents (e.g., camptothecin derivatives) | Hydrolyzed to the corresponding carboxylic acid under basic conditions, followed by amidation or transesterification to construct the active molecular scaffold |
| Organic Synthesis | Structural unit of polymethoxy nitroarenes, used to build analogues of complex natural products | Functional group transformations and carbon skeleton extension via nitro group reduction, diazotization–substitution, and palladium-catalyzed cross-coupling reactions |
Manufacturing Quality Control of Methyl 2-nitro-3,4,5-trimethoxybenzoate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode array detection and spectral comparison against known impurity standards. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents by gas chromatography with flame ionization detection using headspace sampling. |
| Moisture Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine water content based on the stoichiometric reaction between iodine and water. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Combustion at 700-800 C followed by sulfuric acid treatment and weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light in solution to assess chiral purity and identity. |
| Acid Value | Acid-Base Titration | Neutralization of free carboxylic acid groups with standardized NaOH solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue after ignition at 600 C in a muffle furnace per USP <281>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using laser scattering principles and Mie theory. |
Technical Specifications of Methyl 2-nitro-3,4,5-trimethoxybenzoate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 124-128°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 2-nitro-3,4,5-trimethoxybenzoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of Methyl 2-nitro-3,4,5-trimethoxybenzoate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 2-nitro-3,4,5-trimethoxybenzoate
Industrial Methyl 2-nitro-3,4,5-trimethoxybenzoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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