China Factory Direct
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| CAS number | 50820-65-0 |
| Product name | Methyl indole-6-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Used as an organic synthesis intermediate for constructing drug molecules containing indole moieties | Synthesized via esterification or indole ring functionalization; commonly employed as a key building block in multistep synthetic routes |
| Agrochemical Development | Applied as a structural motif in novel insecticides or fungicides | Introduced into bioactive molecules via electrophilic substitution or coupling reactions using methyl indole-6-carboxylate as the core scaffold |
| Chemical Reagents | Used in laboratories for structural modification of indole derivatives and structure–activity relationship (SAR) studies | Employed as a reference standard or reaction substrate in organic transformations such as acylation, reduction, and cyclization |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., indole-6-carboxylic acid, unreacted indole, methyl ester hydrolysis products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace GC analysis with flame ionization detection (or mass spectrometry) to quantify residual methanol, dichloromethane, toluene, or other process solvents per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS or AAS | Quantification of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion; ICP-MS offers multi-element trace-level detection; AAS provides single-element sensitivity. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample water in anhydrous solvent. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration followed by precise weighing of the non-volatile residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement based on optical observation of solid-to-liquid phase change under controlled heating rate (USP <741>). |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers (if applicable); confirms enantiomeric identity and absence of racemization. |
| Appearance and Color | Visual Inspection & APHA Color Scale | Subjective assessment of physical state (crystalline powder), color (white to off-white), and clarity against standardized APHA color solutions. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) to detect acidic/basic degradation products or residual catalysts. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Quantification of chloride ions using suppressed conductivity detection (IC) or argentometric titration with silver nitrate endpoint detection. |
| Sulfated Ash | Gravimetric Analysis | Weight of residue after ignition with sulfuric acid treatment, indicating inorganic sulfate-forming contaminants (USP <281>). |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 128°C - 132°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.