4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5089-33-8 |
| Product name | 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE
| Industry | Application | Process |
|---|---|---|
| Organic Synthesis | Key intermediate for constructing brominated arylamine structures in pharmaceutical molecules | Used as an aryl bromide precursor in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and subjected to deprotection prior to subsequent functional group transformations |
| Pharmaceutical R&D | Synthesis of oncology, anti-inflammatory, and central nervous system-targeted drug candidates | Employed as a nitrogen-protected arylamine building block in multistep total synthesis to suppress side reactions of the amino group under strongly basic or oxidizing conditions, thereby enhancing reaction selectivity |
| Materials Science | Preparation of hole-transport materials for organic light-emitting diodes (OLEDs) and monomers for conjugated polymers | Amine protection with silyl groups enables regioselective coupling at the bromo site; the TMS group is subsequently removed via thermal or acidic cleavage to yield the target amine-functionalized conjugated backbone |
Manufacturing Quality Control of 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., bromoaniline isomers, desilylated products) via gradient HPLC separation and UV response. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile solvents (e.g., toluene, THF, hexane) using gas chromatography with flame ionization detection. |
| Moisture Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration based on iodine consumption in pyridine-methanol buffer. |
| Heavy Metals | ICP-OES | Measures trace metal contaminants (e.g., Fe, Cu, Pb, Ni) after acid digestion by optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Acid Value | Acid-Base Titration | Measures acidic impurities by titration with standardized KOH solution in isopropanol using phenolphthalein indicator. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against white background under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary method per USP <741>. |
| Loss on Drying | Gravimetric Analysis | Measures volatile loss by weighing sample before and after drying at 60 C under vacuum for 2 hours. |
| Residue on Ignition | Sulfated Ash Test | Quantifies non-volatile inorganic residue after high-temperature ignition (700–800 C) following sulfuric acid treatment. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity (if applicable) via rotation of plane-polarized light in solution using sodium D-line. |
Technical Specifications of 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
| Refractive Index (n20/D) | 1.545 - 1.555 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE
Safety Information of 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE
Industrial 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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