8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 50892-62-1 |
| Product name | 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for the antipsychotic drug clozapine | Converted to clozapine via reductive amination, cyclization, and oxidation in the clozapine synthesis pathway |
Manufacturing Quality Control of 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Confirm the consistency of functional groups and molecular framework by comparing the infrared absorption spectra of the sample with that of the reference standard. |
| High-Performance Liquid Chromatography (HPLC) | Use retention time comparison, comparing the sample peak with the reference standard peak to confirm the identity of the target compound. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Quantitatively analyze the main component content using external standard or internal standard methods under specific chromatographic conditions, ensuring compliance with pharmacopoeia standards. |
| Related Substances Test | High-Performance Liquid Chromatography (HPLC) | Separate impurities using gradient or isocratic elution, and calculate the impurity limit using area normalization or self-comparison methods. |
| Dried Weight Loss | Oven Drying Method (105℃ Constant Weight Method) | Dry the sample at a specified temperature until constant weight is achieved, and calculate the percentage of mass loss to assess the moisture and volatile matter content. |
| Residual Carbon | High-Temperature Ashing Method | Weigh the residue after the sample is incinerated at high temperature (typically 700–800℃), to evaluate the total amount of inorganic impurities. |
| Heavy Metal Test | Thioacetamide Method (Chinese Pharmacopoeia) | React under weakly acidic conditions with thioacetamide to produce a color change, and compare with a standard lead solution by colorimetry to control the heavy metal limit. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection, separate organic solvents using capillary columns, and quantify them using FID or ECD detectors. |
| Melting Point Determination | Capillary Melting Point Apparatus Method | Determine the temperature range from initial melting to complete melting, which serves as a physical constant for identification and preliminary purity assessment. |
| pH Value (if applicable) | pH Meter Measurement Method | Prepare a solution of a certain concentration and measure its pH value to evaluate whether the acidity or alkalinity meets formulation or stability requirements. |
Technical Specifications of 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
| Test Item | Specification |
|---|---|
| Appearance | Black solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 192–196 °C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
Safety Information of 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
Industrial 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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