China Factory Direct
|
|
| CAS number | 50909-86-9 |
| Product name | COELENTERAZINE H |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biotechnology / Life Sciences | Substrate in reporter gene assays for measuring luciferase activity | In luciferase reporter assays, coelenterazine-H reacts specifically with recombinant luciferases (e.g., Gaussia luciferase) to generate bioluminescent signals for studies of gene expression, cellular signaling pathways, and high-throughput drug screening |
| Pharmaceuticals | Lead compound screening and target validation in drug discovery | Used in conjunction with luciferase-coupled cells or in vitro systems to assess compound effects on specific biological pathways, enabling high-throughput screening |
| Environmental Monitoring | Biosensor probe for detection of specific pollutants or biomarkers | Integrated with engineered luciferases; changes in luminescence intensity or wavelength respond to target analytes (e.g., metal ions, toxins), supporting real-time environmental monitoring |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at characteristic wavelength using reverse-phase chromatography with calibration against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient elution and UV detection relative to main peak. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents by gas chromatography with flame ionization detection using internal standard or external calibration. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration based on iodine consumption in pyridine/methanol buffer system. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Hg) via mass spectrometric detection of elemental ions after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride anions using suppressed conductivity detection after anion-exchange separation. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion in sulfuric acid medium followed by high-temperature incineration and weighing. |
| Optical Rotation | [a]D Measurement | Determines specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| pH of Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in aqueous suspension or solution using calibrated glass electrode and reference electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension by measuring angular variation in laser light scattering intensity. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms by filtration, membrane transfer to agar media, incubation, and colony enumeration. |
| Residual Catalyst (e.g., Pd) | ICP-OES | Quantifies palladium and other metal catalyst residues by optical emission spectroscopy after microwave-assisted acid digestion. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 225-230°C |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Solubility | Soluble in DMSO and methanol; practically insoluble in water |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.