TOS-PRO-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 51077-01-1 |
| Product name | TOS-PRO-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for TOS-PRO-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk TOS-PRO-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of TOS-PRO-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemistry | Used as a chiral building block or intermediate in drug molecule synthesis | Employed as a chiral auxiliary or ligand in asymmetric catalytic reactions |
| Organic Synthesis | Used to construct complex molecules containing proline structural units | Incorporated into target molecules via amide bond formation, condensation, or coupling reactions |
| Catalytic Chemistry | Used as a chiral ligand precursor in metal-catalyzed asymmetric reactions | Coordinated with transition metals (e.g., copper, palladium) to form chiral catalytic systems |
| Peptide Chemistry | Used to protect proline residues or modify peptide chain structures | Applied as a protected amino acid monomer in solid-phase or solution-phase peptide synthesis |
Manufacturing Quality Control of TOS-PRO-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase and UV detection, resolving L- and D-enantiomers. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing at 700-800 C. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals following acid digestion and plasma emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separation and quantification of sulfate ions using anion-exchange column and conductivity detection. |
| Related Substances | HPLC-UV | Identification and quantification of structurally related impurities (e.g., unreacted L-proline, p-toluenesulfonyl chloride, desulfonylated byproducts) using gradient HPLC. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via capillary tube method observing solid-to-liquid phase change under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength (589 nm). |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on angular variation of laser light scattering intensity. |
Technical Specifications of TOS-PRO-OH
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Purity | >=98.5% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Optical Rotation | -94.0 to -91.0° (c=1, in CHCl3) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of TOS-PRO-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of TOS-PRO-OH
Packaging of TOS-PRO-OH
Industrial TOS-PRO-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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