Ethyl 2-acetyl-3-(dimethylamino)acrylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 51145-57-4 |
| Product name | Ethyl 2-acetyl-3-(dimethylamino)acrylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl 2-acetyl-3-(dimethylamino)acrylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl 2-acetyl-3-(dimethylamino)acrylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl 2-acetyl-3-(dimethylamino)acrylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing anticancer agents (e.g., protein kinase inhibitors) | Undergoes condensation with nitrogen-containing heterocyclic compounds under basic conditions to construct the pyridopyrimidine scaffold |
| Pesticide R&D | Structural building block for novel insecticidal molecules, enabling incorporation of the β-aminocrylate pharmacophore | Undergoes Knoevenagel condensation with aldehydes or palladium-catalyzed cross-coupling with aryl halides |
| Organic Synthesis | Functions as a versatile Michael acceptor and 1,3-biselectrophile in cycloadditions for heterocycle construction | Undergoes addition or cyclization reactions with nucleophiles (e.g., amines, alcohols, active methylene compounds) catalyzed by Lewis acids (e.g., TiCl₄) or organic bases (e.g., DBU) |
Manufacturing Quality Control of Ethyl 2-acetyl-3-(dimethylamino)acrylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 220-254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode-array detection; peak area comparison relative to main peak. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection for quantification of common solvents (e.g., ethanol, DMF, dichloromethane) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water based on stoichiometric reaction. |
| Acid Value | Acid-Base Titration | Titration with standardized potassium hydroxide solution in alcoholic medium to quantify free carboxylic acid or acidic impurities. |
| Color | APHA Color Scale | Visual or spectrophotometric comparison to platinum-cobalt standards to assess yellowness index. |
| Density | Digital Density Meter | Measurement of mass per unit volume at specified temperature (e.g., 20 deg C) using oscillating U-tube principle. |
| Refractive Index | Refractometry | Determination of light bending angle at air-sample interface using calibrated refractometer at controlled temperature. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion using inductively coupled plasma optical emission spectroscopy per USP <231>. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anion in aqueous extract following sample dissolution and dilution. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue after charring and high-temperature ashing (700-800 deg C) per USP <281>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution using sodium D-line. |
Technical Specifications of Ethyl 2-acetyl-3-(dimethylamino)acrylate
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.470–1.480 |
| Relative Density (20°C/25°C) | 1.04–1.06 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl 2-acetyl-3-(dimethylamino)acrylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl 2-acetyl-3-(dimethylamino)acrylate
Safety Information of Ethyl 2-acetyl-3-(dimethylamino)acrylate
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of Ethyl 2-acetyl-3-(dimethylamino)acrylate
Industrial Ethyl 2-acetyl-3-(dimethylamino)acrylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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