BOC-3,4-DEHYDRO-PRO-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 51154-06-4 |
| Product name | BOC-3,4-DEHYDRO-PRO-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-3,4-DEHYDRO-PRO-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-3,4-DEHYDRO-PRO-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-3,4-DEHYDRO-PRO-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthetic intermediate for constructing peptide-based drugs containing dehydroproline motifs and protease inhibitors | Used as a protected amino acid monomer in solid-phase or solution-phase peptide synthesis; participates in amide bond coupling after Boc group deprotection |
| Organic Synthesis | Non-natural α,β-unsaturated amino acid derivative for asymmetric cycloaddition, hydrogenation, and functional group transformations | Applied as a Michael acceptor or Diels–Alder dienophile in Pd/Rh-catalyzed C–C bond formation; also employed in asymmetric hydrogenation to produce chiral saturated proline derivatives |
Manufacturing Quality Control of BOC-3,4-DEHYDRO-PRO-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Chiral Purity | Chiral HPLC | Measures enantiomeric excess by separation on chiral stationary phase and UV detection, comparing retention times and peak areas of enantiomers. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine generated in situ reacting stoichiometrically with water. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., DMF, THF, ethyl acetate) by gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (Pb, Cd, Hg, As, Ni) after acid digestion by optical emission spectroscopy at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after anion exchange separation. |
| Sulfated Ash | Gravimetric Analysis | Determines inorganic residue after high-temperature incineration followed by sulfuric acid treatment and final weighing. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral integrity and concentration-based identity. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine volume-weighted particle size distribution by light scattering pattern analysis. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines pH of 1% w/v aqueous suspension using calibrated glass electrode and pH meter. |
| Related Substances | HPLC-UV (Gradient) | Detects and quantifies structurally related impurities using gradient elution HPLC with UV detection and relative response factor correction. |
| Microbial Limits | Membrane Filtration and Culture | Assesses total aerobic microbial count and absence of specified pathogens (E. coli, Salmonella) by filtration, incubation, and colony enumeration. |
Technical Specifications of BOC-3,4-DEHYDRO-PRO-OH
| Test Item | Specification |
|---|---|
| Appearance | Pale-brown solid |
| Purity | >=98.5% (GC-MS) |
| Optical Rotation | -275.0 to -270.0 deg (c=1, in DMF) |
| Melting Point | 148.0 to 152.0 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-3,4-DEHYDRO-PRO-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-3,4-DEHYDRO-PRO-OH
Packaging of BOC-3,4-DEHYDRO-PRO-OH
Industrial BOC-3,4-DEHYDRO-PRO-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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