Methyl 3-hydroxythiophene-2-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5118-06-9 |
| Product name | Methyl 3-hydroxythiophene-2-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 3-hydroxythiophene-2-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 3-hydroxythiophene-2-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 3-hydroxythiophene-2-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antiviral agents (e.g., ribavirin analogues) | Used to introduce pharmacophoric structures via ester hydrolysis, amidation, or heterocyclic substitution |
| Agrochemicals | Used in the synthesis of biologically active thiophene-based pesticides or herbicides | Applied in electrophilic substitution or metal-catalyzed cross-coupling reactions to construct target molecular frameworks |
| Organic Synthesis | Key building block for constructing thiophene derivatives | Employed for selective functional group transformations—such as reduction, condensation, or cyclization—via its hydroxyl and ester groups |
| Materials Science | Used to prepare precursors for functional organic semiconductor materials | Applied in cross-coupling reactions—including Suzuki or Stille coupling—to form conjugated polymer structures |
Manufacturing Quality Control of Methyl 3-hydroxythiophene-2-carboxylate
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible impurities under natural light or a standard light source. |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with a UV detector (e.g., 254 nm) and a water-organic solvent (e.g., methanol or acetonitrile) gradient elution to quantitatively analyze the content of the target compound. |
| Gas Chromatography (GC) | Suitable for volatile samples. Separation is achieved using a capillary column and FID detection. The sample stability at high temperatures must be confirmed. | |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H-NMR and ¹³C-NMR to confirm the compound structure by comparing characteristic peak chemical shifts with literature values. |
| Mass Spectrometry (MS) | Use ESI or EI ionization methods to determine molecular ion peaks ([M+H]+ or M⁺), verify molecular weight, and assist in structural analysis. | |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Analyze functional group characteristic absorption peaks, such as O-H stretching vibration (~3200 cm⁻¹), C=O (~1700 cm⁻¹), thiophene ring skeletal vibrations, etc. | |
| Moisture Content | Karl Fischer Method | Use electrochemical titration principles to accurately measure trace moisture content in the sample. It includes volumetric and coulometric methods and is suitable for organic compounds with low water content. |
| Residual Solvents | Gas Chromatography (GC) | According to pharmacopoeia requirements (e.g., Chinese Pharmacopoeia, USP), use headspace-GC-FID to detect common residual solvents such as methanol, ethanol, acetone, dichloromethane, etc. |
| Melting Point | Melting Point Determination | Determine the melting point of the compound using capillary method or an automatic melting point instrument, used for preliminary identification and purity evaluation. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine the residue levels of heavy metals such as lead, cadmium, mercury, and arsenic after sample digestion, in compliance with pharmaceutical or chemical safety standards. |
| Ash/Residue on Ignition | Residue on Ignition Method | Weigh the sample after high-temperature carbonization and ashing to determine the total amount of inorganic impurities, commonly used in API quality control. |
| Solubility | Solubility Test | Test the solubility of the sample in different solvents (water, ethanol, methanol, ethyl acetate, etc.) as a reference for physicochemical properties. |
Technical Specifications of Methyl 3-hydroxythiophene-2-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | Brown semi-solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 45–49°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 3-hydroxythiophene-2-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 3-hydroxythiophene-2-carboxylate
Safety Information of Methyl 3-hydroxythiophene-2-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 3-hydroxythiophene-2-carboxylate
Industrial Methyl 3-hydroxythiophene-2-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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