Boc-D-aspartic acid 4-benzyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 51186-58-4 |
| Product name | Boc-D-aspartic acid 4-benzyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Boc-D-aspartic acid 4-benzyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Boc-D-aspartic acid 4-benzyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Boc-D-aspartic acid 4-benzyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral building block for peptide-based drug synthesis | Used as a protected aspartic acid derivative in solid-phase or solution-phase peptide synthesis; introduced via Fmoc/t-Boc strategies, with the α-amino group protected by tert-butoxycarbonyl (Boc) and the side-chain carboxyl group protected by a benzyl ester to enable selective deprotection and coupling reactions |
| Biochemical Research | Synthesis of custom aspartic acid-containing peptides for studying enzyme substrate specificity or protein structure–function relationships | Condensation performed using standard peptide coupling reagents (e.g., HBTU, DIC); Boc deprotection carried out under mild acidic conditions (e.g., TFA), and benzyl ester removal achieved via hydrogenolysis or strong acid treatment |
| Fine Chemicals | High-purity amino acid derivative intermediate for developing novel pharmaceutical intermediates or diagnostic reagents | Produced via asymmetric synthesis or resolution, followed by esterification and Boc protection; purified for subsequent construction of complex molecular frameworks |
Manufacturing Quality Control of Boc-D-aspartic acid 4-benzyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210–220 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., deprotected forms, diastereomers, hydrolysis products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., DMF, DCM, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Optical Rotation | [α]D | Measurement of specific optical rotation at 20 °C using sodium D-line (589 nm) to confirm chiral integrity and enantiomeric identity. |
| Heavy Metals | ICP-MS | Quantification of toxic elements (e.g., Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-MS | Specific quantification of Pd residues (from coupling catalysts) via ICP-MS following microwave-assisted acid digestion. |
| Particle Size Distribution | Laser Diffraction | Determination of dry powder particle size distribution using laser light scattering principles per ISO 13320. |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Mass loss measured after controlled heating (e.g., 105 °C, 2 h) under defined atmospheric conditions. |
| Residual Chloride | Ion Chromatography (IC) | Quantitative analysis of chloride anion using suppressed conductivity detection after aqueous extraction. |
| Microbial Contamination | Membrane Filtration & Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
Technical Specifications of Boc-D-aspartic acid 4-benzyl ester
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +18.0 to +20.5° (c=1, in DMF) |
| Melting Point | 78 to 82°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Boc-D-aspartic acid 4-benzyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Boc-D-aspartic acid 4-benzyl ester
Safety Information of Boc-D-aspartic acid 4-benzyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Boc-D-aspartic acid 4-benzyl ester
Industrial Boc-D-aspartic acid 4-benzyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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