Diosgenin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 512-04-9 |
| Product name | Diosgenin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Diosgenin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Diosgenin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Diosgenin
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Raw material for synthesizing steroid hormones (e.g., cortisol, progesterone, androgens) | DiOSGENIN is extracted from rhizomes of Dioscorea species (e.g., Dioscorea nipponica, Dioscorea zingiberensis) via acid hydrolysis, then chemically modified (e.g., oxidation, rearrangement, esterification) to yield active steroid intermediates |
| Pharmaceutical Intermediates | Used in manufacturing oral contraceptives, anti-inflammatory agents, and hormone replacement therapies | DiOSGENIN undergoes selective deglycosylation, oxidation, epoxidation, and stereoselective reduction to construct the steroid nucleus |
| Chemical Synthesis | Natural steroidal scaffold for total synthesis of complex molecules | Starting from diosgenin, C-17 side-chain modification and A-ring functionalization are performed via enzymatic or chemical catalysis to synthesize high-value steroid compounds |
| Research & Development | Bioactivity screening and structure–activity relationship (SAR) studies | DiOSGENIN is isolated and purified from plant material for in vitro cell assays and in vivo animal models to evaluate hormone receptor binding activity |
Manufacturing Quality Control of Diosgenin
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies diosgenin content by separation on a reversed-phase column and UV detection at 205-210 nm. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone) by gas chromatography with flame ionization detection. |
| Heavy Metals | AAS | Determines total heavy metals (Pb, Cd, As, Hg) after acid digestion using atomic absorption spectroscopy. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after combustion with sulfuric acid treatment and high-temperature incineration. |
| Loss on Drying | Thermogravimetric Analysis | Determines volatile content by weight loss upon heating at 105 C under controlled conditions. |
| Specific Optical Rotation | Polarimetry | Measures optical activity using sodium D-line light to confirm chiral integrity and identity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition as an identity and purity indicator. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of powder particles in suspension using light scattering principles. |
| Water Content | Karl Fischer Titration | Quantifies trace water by volumetric or coulometric titration with iodine-based reagent. |
| Microbial Limits | Membrane Filtration | Evaluates total aerobic microbial count and absence of specified pathogens per pharmacopeial methods. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in a standardized aqueous slurry using calibrated pH electrode. |
Technical Specifications of Diosgenin
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Purity | >=98.0% (NMR) |
| Melting Point | 204–208 °C |
| Optical Rotation | -123 to -127 ° (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Diosgenin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Diosgenin
Packaging of Diosgenin
Industrial Diosgenin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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