5-Chloropyridine-3-carboxylic acid methyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 51269-81-9 |
| Product name | 5-Chloropyridine-3-carboxylic acid methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Chloropyridine-3-carboxylic acid methyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Chloropyridine-3-carboxylic acid methyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Chloropyridine-3-carboxylic acid methyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key synthetic building block for preparing centrally active pharmaceutical molecules (e.g., selective phosphodiesterase inhibitors), enabling drug scaffold construction via coupling or functional group transformation reactions. |
| Agrochemicals | Agrochemical Intermediates | Used in the synthesis of pyridine-ring-containing or neonicotinoid agrochemicals; the reactivity of the chlorine atom facilitates nucleophilic substitution to introduce bioactive functional groups for insecticide or fungicide production. |
| Organic Synthesis | Fine Chemical Feedstock | Functions as a bifunctional substrate—leveraging the dual reactivity of the ester group and chlorine atom—in Suzuki coupling or amination reactions to construct complex nitrogen-containing heterocyclic compounds. |
Manufacturing Quality Control of 5-Chloropyridine-3-carboxylic acid methyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., methanol, dichloromethane) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of metallic impurities (e.g., Pb, Cd, Ni) after acid digestion, using inductively coupled plasma optical emission spectrometry. |
| Chloride Ion Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Acid Value | Acid-Base Titration | Neutralization of free acid impurities with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint detection. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic residue after high-temperature incineration at 700-800 C followed by weighing of the cooled crucible. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change in a capillary tube under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light caused by chiral impurities or enantiomeric excess, using sodium D-line light source. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in dry or dispersed state by measuring angular variation in laser light scattering. |
| Bulk Density | Tap Density Measurement | Determination of mass per unit volume after mechanical tapping of a known mass in a calibrated cylinder. |
Technical Specifications of 5-Chloropyridine-3-carboxylic acid methyl ester
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Chloropyridine-3-carboxylic acid methyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Chloropyridine-3-carboxylic acid methyl ester
Safety Information of 5-Chloropyridine-3-carboxylic acid methyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-Chloropyridine-3-carboxylic acid methyl ester
Industrial 5-Chloropyridine-3-carboxylic acid methyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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