4-Bromo-2-fluorotoluene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 51436-99-8 |
| Product name | 4-Bromo-2-fluorotoluene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromo-2-fluorotoluene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromo-2-fluorotoluene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromo-2-fluorotoluene
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate for synthesizing biologically active fluorinated and brominated aromatic compounds | Fluorine or bromine substituents are introduced via electrophilic substitution or metal-catalyzed coupling reactions (e.g., Suzuki, Ullmann) to construct complex molecular frameworks |
| Agrochemicals | Employed as a structural building block for novel fungicides or insecticides | 2-Fluoro-4-bromotoluene serves as a key intermediate in heterocyclic system construction through halogen exchange or directed functionalization reactions |
| Materials Science | Utilized as a precursor for liquid crystal materials or organic light-emitting diode (OLED) materials | Aromatic rings are coupled via transition metal-catalyzed reactions (e.g., Heck, Stille) to form conjugated systems |
| Chemical Research | Serves as a model compound in organic synthesis for studying halogen-directed effects and C–H activation | Applied to investigate regioselective substitution reactions, directing group effects, and optimization of multistep synthetic routes |
Manufacturing Quality Control of 4-Bromo-2-fluorotoluene
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, state, and presence of visible impurities under natural or standard lighting. 2-Fluoro-4-bromo-toluene is typically a clear to slightly yellow transparent liquid. |
| Purity | Gas Chromatography (GC) | Use capillary column gas chromatography with an FID detector to quantitatively analyze the main component content. Purity is calculated by area normalization or internal standard method. Common chromatographic conditions include DB-5 or HP-5 columns with temperature programming. |
| Water Content | Karl Fischer Titration | Determine water content by quantitative reaction with KF reagent. The water content is measured by coulometric or volumetric titration, suitable for precise determination of trace water in organic solvents. |
| Boiling Point/Range | Distillation Method (e.g., micro boiling point apparatus or atmospheric distillation) | Determine the initial boiling point and dry point under standard atmospheric pressure to evaluate volatility consistency. Meets specification requirements (2-Fluoro-4-bromo-toluene boiling point is approximately 190–192 °C). |
| Refractive Index | Abbe Refractometer Method | Measure the refractive index of the sample at a specified temperature (usually 20 °C or 25 °C), used for identification and purity assessment. Typical value is about 1.530–1.540. |
| Density | Pycnometer Method or Digital Density Meter | Measure the sample density at standard temperature. The density of 2-Fluoro-4-bromo-toluene is approximately 1.48–1.52 g/cm³, which can serve as one of the quality control indicators. |
| Residual Solvents | Headspace-Gas Chromatography (HS-GC) | Analyze residual organic solvents (e.g., toluene, methylene chloride) possibly present from the manufacturing process using headspace sampling combined with GC-FID or GC-MS. Must comply with ICH Q3C limits. |
| Related Substances (Impurities) | Gas Chromatography-Mass Spectrometry (GC-MS) or High-Performance Liquid Chromatography (HPLC) | GC-MS is used for identification and quantification of volatile organic impurities; HPLC (e.g., C18 reversed-phase column with UV detection) is suitable for analysis of non-volatile or thermally unstable impurities, ensuring total impurity content meets standards (typically ≤0.5%). |
| Elemental Impurities (e.g., Bromine, Fluorine Content) | Ion Chromatography (IC) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Determine halogen or metal element content after sample digestion to verify molecular composition consistency and absence of harmful elemental impurities. |
Technical Specifications of 4-Bromo-2-fluorotoluene
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.535–1.545 |
| Relative Density (20°C/25°C) | 1.47–1.49 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromo-2-fluorotoluene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromo-2-fluorotoluene
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Industrial 4-Bromo-2-fluorotoluene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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