China Factory Direct
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| CAS number | 518-18-3 |
| Product name | (+/-)-EvodiaMine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Research | Study of bioactive constituents in natural products | Used in laboratory research for pharmacological activities including anti-inflammatory, analgesic, and anticancer effects |
| Pharmaceutical Research | Quality control and analysis of traditional Chinese medicines (TCMs) | Applied as a reference standard for quality testing and quantitative analysis of TCMs such as Evodiae Fructus |
| Biochemistry | Cell signaling pathway research | Applied in in vitro experiments to investigate regulatory mechanisms of signaling pathways including JAK/STAT and NF-κB |
| Drug Development | Lead compound for antitumor agents | Used in structural modification and structure–activity relationship (SAR) studies to support the design of novel anticancer drugs |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies (±)-evodiamine content using reversed-phase HPLC with UV detection at 225 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Detects and quantifies structurally similar impurities by HPLC with diode-array detection, using gradient elution and peak purity assessment. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, ethyl acetate) via gas chromatography with flame ionization detection against calibrated standards. |
| Heavy Metals | ICP-MS | Determines total heavy metal content (Pb, Cd, As, Hg, Ni) by inductively coupled plasma mass spectrometry after acid digestion. |
| Water Content | Karl Fischer Titration | Quantifies water by volumetric or coulometric titration using iodine-based reagent, based on the stoichiometric reaction of water with iodine and sulfur dioxide. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic residue after high-temperature ashing (700–800 C) and weighing of the cooled crucible. |
| Specific Optical Rotation | Polarimetry | Measures optical activity using sodium D-line light to assess enantiomeric composition and detect chiral impurities. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in suspension using Mie scattering theory and laser diffraction principles. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli, Salmonella) by filtration, incubation, and colony enumeration. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Organic Volatile Impurities (OVI) | GC-MS | Identifies and quantifies genotoxic impurities and residual synthesis intermediates using gas chromatography coupled with mass spectrometry. |
| Test Item | Specification |
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| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -10° to +10° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.