Podophyllotoxin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 518-28-5 |
| Product name | Podophyllotoxin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Podophyllotoxin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Podophyllotoxin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Podophyllotoxin
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Development | Development of antitumor agents | Used as an intermediate in the synthesis of complex drug molecules |
| Natural Products Research | Investigation of biological activity and molecular structure | Extraction and purification processes |
| Organic Synthesis | Synthesis of other organic compounds | Organic synthesis reactions |
| Pesticide Development | Development of novel pesticides | Synthesis and structural modification processes |
| Biotechnology | Cell culture and screening | Cell culture and bioactivity screening processes |
Manufacturing Quality Control of Podophyllotoxin
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Utilizes the characteristic absorption peak of podophyllotoxin at a specific wavelength (e.g., around 290 nm) for qualitative identification. |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Confirms consistency in functional groups and molecular structure by comparing the infrared absorption spectra of the sample with those of the reference standard. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, and UV detection (around 290 nm) for quantitative analysis of podophyllotoxin content. Offers high sensitivity and accuracy. |
| Ultraviolet Spectrophotometry (UV) | Determines absorbance at the maximum absorption wavelength and calculates content based on a standard curve. Simple to operate but has lower specificity, suitable for preliminary determination of crude extracts. | |
| Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Checks related substances such as isomers and degradation products to assess sample purity. Gradient elution is often used to enhance separation efficiency. |
| Residual Solvents | Gas Chromatography (GC) | Detects residual organic solvents (e.g., methanol, ethanol, acetone) from extraction or synthesis processes, ensuring compliance with pharmacopoeial limits for residual solvents. |
| Water Content | Karl Fischer Titration | Accurately determines the moisture content in samples, suitable for quality control of active pharmaceutical ingredients. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Measures levels of harmful heavy metals such as lead, cadmium, and arsenic to ensure compliance with pharmaceutical safety standards. |
| Microbial Limits | Microbial Limit Test | Conducted according to requirements of the Chinese Pharmacopoeia or international pharmacopoeias, testing for bacteria, molds, yeasts, and specified control organisms (e.g., Escherichia coli) to ensure microbial safety. |
Technical Specifications of Podophyllotoxin
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 135.0–139.0 °C |
| Optical Rotation | -112.0 to -108.0 ° (c=1, in chloroform) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Podophyllotoxin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Podophyllotoxin
Packaging of Podophyllotoxin
Industrial Podophyllotoxin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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