2-(1-AMINO-1-METHYLETHYL)-N-(4-FLUOROBENZYL)-5-HYDROXY-1-METHYL-6-OXO-1,6-DIHYDROPYRIMIDINE-4-CARBOXAMIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 518048-03-8 |
| Product name | 2-(1-AMINO-1-METHYLETHYL)-N-(4-FLUOROBENZYL)-5-HYDROXY-1-METHYL-6-OXO-1,6-DIHYDROPYRIMIDINE-4-CARBOXAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 518048-03-8
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 518048-03-8 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 518048-03-8
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antiviral drugs | Organic synthesis and structural modification |
| Biochemical Research | Study of biologically active molecules | Chemical synthesis and purification |
| Pharmaceutical Manufacturing | Synthesis of antiviral compounds | Multi-step organic reactions and catalytic processes |
Manufacturing Quality Control of 518048-03-8
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of lumps under natural light or standard illumination to determine if it meets specified characteristics (e.g., white to off-white powder). |
| Identification | High-Performance Liquid Chromatography (HPLC) | Confirm the presence of the target compound by comparing retention times with reference standards; typically uses a reversed-phase C18 column and UV detection. |
| Identification | Mass Spectrometry (MS or LC-MS) | Determine the molecular ion peak to confirm molecular weight (theoretical molecular weight ~413.4 g/mol), verifying structural consistency. |
| Identification | Nuclear Magnetic Resonance Spectroscopy (¹H-NMR and ¹³C-NMR) | Confirm chemical structure through characteristic chemical shifts and splitting patterns; commonly used for starting materials or key intermediates. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Quantify the main component using external standard or internal standard method. Typically employs a C18 column with gradient or isocratic elution and UV detection (e.g., 254 nm or 280 nm), calculating concentration based on peak area. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Detect process-related impurities and degradation products. High-resolution chromatographic conditions are used to separate individual impurity peaks; UV detection is applied, with impurity total and individual impurity levels calculated using self-reference or area normalization methods. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvent residues from manufacturing processes (e.g., methanol, ethanol, dichloromethane, DMF). Limits follow ICH Q3C guidelines; headspace injection with GC-FID detection is typically used. |
| Water Content | Karl Fischer Titration | Determine total water content (combined and free water) via volumetric or coulometric Karl Fischer titration, ensuring compliance with storage and formulation requirements. |
| Residue on Ignition | Residue on Ignition Test Method | After high-temperature ashing, weigh the residue to assess inorganic impurity levels; commonly applied to active pharmaceutical ingredients. |
| Heavy Metals | Heavy Metal Testing (e.g., Sulfide Method or ICP-MS) | Detect toxic heavy metals such as lead, cadmium, mercury, and arsenic using colorimetric methods or inductively coupled plasma mass spectrometry (ICP-MS), meeting pharmacopoeial or ICH Q3D requirements. |
| Polymorphism Analysis | X-Ray Powder Diffraction (XRPD) | Distinguish between different polymorphic forms to ensure batch-to-batch consistency, as crystal form affects solubility and stability. |
| Particle Size Distribution | Laser Diffraction (LD) | Assess particle size distribution of raw materials, which influences formulation uniformity and dissolution behavior. |
| Melting Point | Melting Point Determination (Capillary Method or DSC) | Determine melting temperature using differential scanning calorimetry (DSC) or conventional capillary method, aiding in identification and purity assessment. |
Technical Specifications of 518048-03-8
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 218–222°C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 518048-03-8
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 518048-03-8
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Industrial 518048-03-8 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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