N-BOC-1,6-diaminohexane Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 51857-17-1 |
| Product name | N-BOC-1,6-diaminohexane |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-BOC-1,6-diaminohexane
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-BOC-1,6-diaminohexane Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-BOC-1,6-diaminohexane
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Amino acid protecting reagent for temporary protection of the lysine side-chain amino group in peptide synthesis | Prepared via reaction of isocyanate with 6-aminohexylamine in solid-phase peptide synthesis (SPPS), followed by coupling to the carboxyl group of the target amino acid or peptide chain; the tert-butoxycarbonyl (Boc) group is selectively removed under acidic conditions (e.g., TFA) |
| Organic Synthesis | Multifunctional amino-based linker for constructing PROTAC molecules, antibody–drug conjugate (ADC) linkers, and targeted probes | Used as a spacer to connect the target protein ligand and the E3 ligase ligand (in PROTACs) or to link the antibody and cytotoxic payload (in ADCs); typically incorporated into the molecular scaffold via amidation, urea formation, or thiourea formation |
Manufacturing Quality Control of N-BOC-1,6-diaminohexane
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 200-220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities by gradient HPLC-UV; identification and quantification against reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., THF, DMF, toluene) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction with water. |
| Residual Metals (e.g., Pd, Ni, Fe) | ICP-MS | Multi-element quantification after acid digestion using inductively coupled plasma mass spectrometry for ultra-trace metal impurities. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration. |
| Heavy Metals (Total) | AAS (Flame or Graphite Furnace) | Acid digestion followed by atomic absorption spectroscopy to measure total heavy metals (e.g., Pb, Cd, Hg) as sulfide precipitate limit test equivalent. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using sodium D-line light source to confirm chiral integrity and absence of racemization. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition analysis by observing solid-to-liquid phase change in capillary tube under controlled heating rate. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Weight loss measurement after drying under standardized temperature and time to determine volatile and moisture content. |
| pH of Aqueous Solution | pH Meter | Measurement of hydrogen ion activity in a defined aqueous suspension or solution using calibrated glass electrode. |
| Residual tert-Butyl Carbamate | GC-MS | Detection and quantification of thermal decomposition product (tert-butyl carbamate) using gas chromatography coupled with mass spectrometry. |
Technical Specifications of N-BOC-1,6-diaminohexane
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic, mild |
| Solubility | Soluble in common organic solvents (e.g., dichloromethane, ethyl acetate, methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-BOC-1,6-diaminohexane
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-BOC-1,6-diaminohexane
Packaging of N-BOC-1,6-diaminohexane
Industrial N-BOC-1,6-diaminohexane Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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