China Factory Direct
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| CAS number | 51887-89-9 |
| Product name | 3-CHLORO-L-ALANINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antibiotics (e.g., chloramphenicol-class compounds) | Used as a chiral building block in multistep organic synthesis to construct chlorinated amino acid structural units |
| Pharmaceuticals | Precursor for antitumor drug synthesis | Introduced as a chloroalanine residue in solid-phase or solution-phase peptide synthesis for developing targeted therapeutics |
| Biochemical Research | Tool for enzyme inhibitor studies | Employed to prepare mechanism-based probes that specifically inhibit serine/cysteine proteases |
| Agrochemicals | Chiral intermediate for pesticide synthesis | Applied in asymmetric synthesis processes to build biologically active chlorinated amino acid derivatives |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Optical Rotation | [alpha]D | Measurement of specific rotation using a polarimeter at 20 degrees C with sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Chloride Content | Potentiometric Titration with AgNO3 | Direct titration with standardized silver nitrate solution using a silver indicator electrode to determine total chloride ion concentration. |
| Residual Solvents | GC-FID | Separation and quantification of common organic solvents (e.g., methanol, acetone, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric determination of water based on the stoichiometric reaction between iodine, sulfur dioxide, and water in pyridine/methanol medium. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., L-alanine, glycine, chloroacetic acid) using gradient HPLC-UV against qualified reference standards. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of pH in a 1% w/v aqueous solution using a calibrated pH meter with glass electrode. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 degrees C followed by weighing of residual inorganic sulfate ash after treatment with sulfuric acid. |
| Loss on Drying | Thermogravimetric Analysis | Measurement of weight loss upon heating at 105 degrees C for 2 hours under vacuum or dry air to determine volatile content including residual moisture and solvents. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, Salmonella) per pharmacopeial guidelines. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | -12.0° to -14.0° (c=1, 6N HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.