DL-PENICILLAMINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 52-66-4 |
| Product name | DL-PENICILLAMINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for DL-PENICILLAMINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk DL-PENICILLAMINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of DL-PENICILLAMINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Treatment of Wilson’s disease (copper metabolism disorder), rheumatoid arthritis, and cystinuria | Administered orally as a copper chelator or immunomodulator; promotes excretion by forming stable complexes with metal ions (e.g., Cu²⁺) |
| Pharmaceuticals | Antidote for heavy metal poisoning (e.g., lead, mercury, arsenic) | Administered intravenously or orally; binds heavy metal ions via thiol groups to form non-toxic, water-soluble complexes excreted renally |
| Biochemical Research | Reducing agent for protein and peptide structural analysis | Used in the laboratory to cleave disulfide bonds (–S–S–), inducing protein denaturation and unfolding to facilitate sequencing or electrophoretic analysis |
| Chemical Industry | Chiral resolving agent | Employed as a chiral ligand or derivatizing reagent in chromatographic methods (e.g., HPLC) to separate enantiomers in racemic mixtures |
Manufacturing Quality Control of DL-PENICILLAMINE
| Test Item | Commonly Used Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectrophotometry (IR) | Confirm the molecular structure by comparing the sample spectrum with a reference spectrum based on characteristic absorption peaks. |
| Chemical Color Reaction | Use the reaction between penicillamine and specific reagents (e.g., ninhydrin) to produce a color change for preliminary identification. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column (e.g., C18) and a UV detector (around 210 nm), with external or internal standard method for quantification. |
| Non-Aqueous Titration | Titrate in a non-aqueous solvent (e.g., glacial acetic acid) using a perchloric acid standard solution; suitable for assay of active pharmaceutical ingredients. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate impurities using gradient elution, check the resolution between the main and impurity peaks, and determine impurity limits in accordance with ICH requirements. |
| Water Content | Karl Fischer Method | Precisely determine the moisture content in the sample by coulometric or volumetric methods; suitable for trace moisture analysis. |
| Sulfated Ash | Sulfated Ash Test | Ignite the sample at high temperature (700–800°C), weigh the residue to evaluate the content of inorganic impurities. |
| Heavy Metals | Sulfide Colorimetric Method (Chinese Pharmacopoeia Method) | In acidic conditions, heavy metals react with hydrogen sulfide to form colored precipitates; colorimetric method used to determine total heavy metal limits. |
| Solution Clarity and Color | Visual Turbidity/Color Comparison Method | Dissolve the sample and compare it with standard turbidity or color solutions to assess clarity and color conformity. |
| pH Value | pH Meter Method | Prepare an aqueous solution of defined concentration and measure the acidity or alkalinity using a calibrated pH meter. |
| Specific Optical Rotation | Polarimetry | Measure the optical rotation at a specific wavelength (e.g., sodium D-line) using a polarimeter to determine the proportion of D/L isomers. |
Technical Specifications of DL-PENICILLAMINE
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 187-191°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -24.5° to -26.5° (c=1, H2O) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of DL-PENICILLAMINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of DL-PENICILLAMINE
Packaging of DL-PENICILLAMINE
Industrial DL-PENICILLAMINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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