Apigenin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 520-36-5 |
| Product name | Apigenin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Apigenin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Apigenin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Apigenin
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Active pharmaceutical ingredient for adjuvant antitumor therapy | Induces apoptosis and inhibits tumor cell proliferation and metastasis |
| Pharmaceutical Industry | Anti-inflammatory and antiallergic agent | Suppresses expression and release of proinflammatory cytokines (e.g., TNF-α, IL-6) and modulates immune responses |
| Pharmaceutical Industry | Neuroprotective agent | Crosses the blood–brain barrier to reduce neuronal oxidative damage and improve cognitive function and memory |
| Dietary Supplements | Natural sedative and sleep aid | Modulates the central nervous system via GABA receptor interaction to alleviate anxiety and insomnia |
| Dietary Supplements | Functional ingredient for blood pressure and lipid regulation | Promotes vasodilation, inhibits vascular smooth muscle cell proliferation, and regulates lipid metabolism |
| Cosmetics Industry | Skin-brightening additive | Inhibits tyrosinase activity to block melanin synthesis and reduce hyperpigmentation |
| Cosmetics Industry | Antioxidant and anti-aging agent | Scavenges free radicals, activates the Nrf2 signaling pathway, and mitigates UV-induced skin photoaging |
| Cosmetics Industry | Sunscreen synergist | Absorbs a portion of UV radiation to reduce phototoxicity and photosensitivity reactions |
| Functional Foods | Natural food preservative | Leverages antioxidant properties to delay oxidative rancidity in lipid-rich foods |
| Functional Foods | Food antioxidant additive | Added to oils or food systems to prevent oxidative degradation of components |
| Scientific Research | Biochemical tool reagent | Serves as a protein kinase (e.g., CK2) inhibitor for studying cellular signal transduction pathways |
| Scientific Research | Fluorescent probe material | Utilizes intrinsic fluorescence for labeling and analytical detection of biomacromolecules |
Manufacturing Quality Control of Apigenin
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies apigenin by separation on a reversed-phase column and UV detection at ~335 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Detects and semi-quantifies structurally related impurities (e.g., luteolin, chrysin) using diode-array detection and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, ethyl acetate) by gas chromatography with flame ionization detection against calibrated standards. |
| Heavy Metals (Total) | ICP-OES | Determines total content of toxic elements (Pb, Cd, As, Hg, Cr) after acid digestion by inductively coupled plasma optical emission spectrometry. |
| Loss on Drying | Gravimetric (105 C) | Measures volatile matter including water and residual solvents by weight loss after drying at 105 C for 2 hours under controlled conditions. |
| Residue on Ignition | Gravimetric (500-600 C) | Quantifies inorganic ash content by weighing residue remaining after high-temperature ignition of the sample. |
| Specific Optical Rotation | Polarimetry | Measures the angle of rotation of plane-polarized light induced by chiral centers in apigenin solution, indicating enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid apigenin transitions to liquid, confirming identity and crystallinity. |
| Solubility Profile | Visual Observation in Standard Solvents | Evaluates qualitative solubility in water, ethanol, methanol, chloroform, and DMSO per USP/EP general chapter <781>. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of powder particles in suspension using Mie scattering theory and calibrated instrument optics. |
| Microbial Limits | Membrane Filtration + Culture | Quantifies aerobic mesophilic microorganisms and detects specified pathogens (e.g., E. coli, Salmonella) by filtration, incubation, and colony enumeration. |
| Water Content | Karl Fischer Titration | Determines trace water content via coulometric or volumetric titration using iodine generated electrochemically in a pyridine-methanol solvent system. |
Technical Specifications of Apigenin
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 335–337°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Apigenin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Apigenin
Packaging of Apigenin
Industrial Apigenin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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