China Factory Direct
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| CAS number | 52175-10-7 |
| Product name | Adenine phosphate(1:x) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antiviral drugs (e.g., adefovir, tenofovir, and other nucleoside analogues) | Used to introduce the adenine phosphate structure via chemical synthesis or enzyme-catalyzed reactions for nucleotide prodrug construction |
| Biotechnology | RNA synthesis substrate component in in vitro transcription (IVT) reaction systems | Participates in the in vitro synthesis of mRNA or non-coding RNA under RNA polymerase catalysis |
| Molecular Biology | Reference standard or calibration standard for nucleic acid metabolism studies and HPLC/MS analysis | Dissolved and prepared for quantitative and qualitative analysis in chromatographic or mass spectrometric detection methods |
| Diagnostics | Control material in nucleic acid amplification assay reagents (e.g., RT-PCR) | Blended with other nucleotides to formulate positive control templates or internal standards |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 260 nm based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and control per ICH Q3B thresholds. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (Pb, Cd, As, Hg, Ni) after acid digestion, with detection at sub-ppt levels. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against NaCl calibration curve. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate ions; quantified against K2SO4 calibration curve. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in a standardized aqueous solution at 25 C. |
| Appearance | Visual Inspection | Assessment of color and clarity against water-white standard under controlled white light and against specified USP/EP visual standards. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of non-volatile inorganic residue after cooling in desiccator. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, Salmonella) per Ph. Eur. 2.6.12. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values per ISO 13320. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.